Безопасен ли troxerutin при беременности?

Безопасные альтернативы troxerutin при беременности | VeriMom

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Безопасен ли troxerutin при беременности?

Human epidemiological data (population case–control) linking oral hydroxyethylrutoside treatment during early pregnancy to increased risk of specific congenital abnormalities supports a 'suspected' reproductive hazard (see Pósfai et al. 2014). No harmonised CLP/SCCS/CIR reproductive classification for troxerutin was found. For topical cosmetic use dermal systemic exposure is expected to be negligible given troxerutin's high molecular weight and hydrophilicity, so exposure from cosmetics is rated negligible.

Безопасен ли troxerutin при грудном вскармливании?

Animal reports indicate traces of hydroxyethylrutosides can be found in milk after systemic (oral) dosing; combined with the human epidemiology above this supports a suspected hazard for systemic use. For topical cosmetic use in the mother, systemic absorption is expected to be negligible and transfer via breast milk from topical use is considered negligible.

Безопасен ли troxerutin для кожи малыша?

Hazard is retained (suspected) because evidence exists for reproductive/ developmental effects with systemic exposures to hydroxyethylrutosides. Mechanistic reproductive toxicity data specific to troxerutin were not found. Dermal absorption from cosmetic use is expected to be very low in adults (e=0), but infant (0–3 yr) skin has increased permeability and higher surface-area-to-weight, so exposure is increased by +1 (e=1) compared with adults despite limited direct absorption data.

Как VeriMom оценивает troxerutin?

VeriMom оценивает troxerutin в 60/100 (средний риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы troxerutin при беременности?

См. наш список безопасных альтернатив troxerutin с аналогичной функцией и классификацией без известных рисков.