VeriMomБезопасен ли trimethyl-3-cyclopentenylacetonitrile при беременности?
No harmonised CLP classification or regulatory reproductive hazard was identified; the RIFM (peer‑reviewed, Food and Chemical Toxicology 2019) safety assessment reports a developmental/reproductive NOAEL = 500 mg/kg/day and concludes the material is safe as used in fragrances, with margins of exposure based on read‑across showing MOE >100. No mechanistic reproductive/toxic endocrine activity was reported. Dermal cosmetic exposure is expected to be low but measurable. ([fragrancematerialsafetyresource.elsevier.com](https://fragrancematerialsafetyresource.elsevier.com/sites/default/files/15373-31-6.pdf))
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Frequently asked questions
- Безопасен ли trimethyl-3-cyclopentenylacetonitrile при беременности?
- No harmonised CLP classification or regulatory reproductive hazard was identified; the RIFM (peer‑reviewed, Food and Chemical Toxicology 2019) safety assessment reports a developmental/reproductive NOAEL = 500 mg/kg/day and concludes the material is safe as used in fragrances, with margins of exposure based on read‑across showing MOE >100. No mechanistic reproductive/toxic endocrine activity was reported. Dermal cosmetic exposure is expected to be low but measurable. ([fragrancematerialsafetyresource.elsevier.com](https://fragrancematerialsafetyresource.elsevier.com/sites/default/files/15373-31-6.pdf))
- Безопасен ли trimethyl-3-cyclopentenylacetonitrile при грудном вскармливании?
- No data or regulatory classification indicating effects on lactation or pup exposure were found; the RIFM assessment found no developmental/reproductive hazard at high NOAELs and did not report evidence of transfer/lactational toxicity. Therefore hazard and mechanism are scored 0; exposure from maternal topical cosmetic use is assessed as low but potentially measurable. ([fragrancematerialsafetyresource.elsevier.com](https://fragrancematerialsafetyresource.elsevier.com/sites/default/files/15373-31-6.pdf))
- Безопасен ли trimethyl-3-cyclopentenylacetonitrile для кожи малыша?
- No infant‑specific reproductive or developmental toxicity was identified. Because RIFM/PubChem characterize this as a fragrance ingredient with measurable dermal exposure potential and log Kow ~3.3 (moderate lipophilicity), apply the protocol’s +1 exposure increment for infants: adult exposure scored as low (1) → baby exposure scored as moderate (2). No infant‑specific hazard or mechanism data were located. ([fragrancematerialsafetyresource.elsevier.com](https://fragrancematerialsafetyresource.elsevier.com/sites/default/files/15373-31-6.pdf))
- Как VeriMom оценивает trimethyl-3-cyclopentenylacetonitrile?
- VeriMom оценивает trimethyl-3-cyclopentenylacetonitrile в 93/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы trimethyl-3-cyclopentenylacetonitrile при беременности?
- См. наш список безопасных альтернатив trimethyl-3-cyclopentenylacetonitrile с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.