VeriMomБезопасен ли r-clostridium histolyticum collagenase g при беременности?
No harmonised reproductive hazard (H360/H361) for C. histolyticum collagenase was found. Clinical and regulatory sources (drug monographs / FDA/EMA product information and PubMed clinical literature) describe local enzymatic effects and injection-site risks but do not report developmental or teratogenic effects; no CIR or SCCS safety assessment for cosmetic topical use was identified. Sources: clinical drug monographs and PubMed summaries show use as an injected medical product without reproductive classification. ([drugs.com](https://www.drugs.com/monograph/collagenase-clostridium-histolyticum.html?utm_source=openai))
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Frequently asked questions
- Безопасен ли r-clostridium histolyticum collagenase g при беременности?
- No harmonised reproductive hazard (H360/H361) for C. histolyticum collagenase was found. Clinical and regulatory sources (drug monographs / FDA/EMA product information and PubMed clinical literature) describe local enzymatic effects and injection-site risks but do not report developmental or teratogenic effects; no CIR or SCCS safety assessment for cosmetic topical use was identified. Sources: clinical drug monographs and PubMed summaries show use as an injected medical product without reproductive classification. ([drugs.com](https://www.drugs.com/monograph/collagenase-clostridium-histolyticum.html?utm_source=openai))
- Безопасен ли r-clostridium histolyticum collagenase g при грудном вскармливании?
- No evidence in peer‑reviewed literature or regulatory monographs of effects on lactation or transfer in breastmilk. As a high‑molecular‑weight protein/enzyme used in injectable formulations, systemic exposure in cosmetic topical use is expected to be negligible; no studies showing breastmilk transfer or lactation toxicity were located. ([drugs.com](https://www.drugs.com/monograph/collagenase-clostridium-histolyticum.html?utm_source=openai))
- Безопасен ли r-clostridium histolyticum collagenase g для кожи малыша?
- Hazard and mechanism: no infant‑specific reproductive or developmental toxicity evidence was found (h=0, m=0). Exposure: dermal absorption of large enzymes is expected to be negligible in adults (e=0) but, per your calibration rule, infant/0–3 y skin barrier immaturity increases exposure rating by +1 to e=1 if the ingredient has measurable absorption potential. Enzyme products and SDSs emphasise respiratory sensitisation risk (inhalation) rather than dermal systemic toxicity. No baby‑specific studies located. ([sigmaaldrich.com](https://www.sigmaaldrich.com/catalog/product/roche/collhro?utm_source=openai))
- Как VeriMom оценивает r-clostridium histolyticum collagenase g?
- VeriMom оценивает r-clostridium histolyticum collagenase g в 100/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы r-clostridium histolyticum collagenase g при беременности?
- См. наш список безопасных альтернатив r-clostridium histolyticum collagenase g с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.