VeriMomБезопасен ли pueraria lobata root extract при беременности?
Pueraria lobata root extract contains isoflavones (notably puerarin, daidzein, genistein) that show estrogenic activity in vitro and have produced reproductive/anti‑implantation effects in animal studies (rats). These animal reproductive findings justify a 'suspected' reproductive hazard (h=2) and indicate a demonstrated endocrine mechanism (m=2). Dermal exposure from cosmetics is expected to be low but measurable (e=1). Sources: Reproduction (puerarin disrupts pregnancy in rats) and in vitro estrogenic studies. (see sources).
Pregnancy-safe products containing pueraria lobata root extract
Безопасные альтернативы pueraria lobata root extract при беременности | VeriMom
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Frequently asked questions
- Безопасен ли pueraria lobata root extract при беременности?
- Pueraria lobata root extract contains isoflavones (notably puerarin, daidzein, genistein) that show estrogenic activity in vitro and have produced reproductive/anti‑implantation effects in animal studies (rats). These animal reproductive findings justify a 'suspected' reproductive hazard (h=2) and indicate a demonstrated endocrine mechanism (m=2). Dermal exposure from cosmetics is expected to be low but measurable (e=1). Sources: Reproduction (puerarin disrupts pregnancy in rats) and in vitro estrogenic studies. (see sources).
- Безопасен ли pueraria lobata root extract при грудном вскармливании?
- Same hazard and mechanism apply for lactating people because the active constituents are phytoestrogens with demonstrated endocrine activity in animals/in vitro. Topical application to the breast would give low but measurable exposure to the parent; systemic transfer into milk is plausible for small lipophilic isoflavones but direct human lactation data are lacking, so exposure is rated low (e=1). Animal reproductive/lactation-specific data are limited. See cited animal and in vitro studies.
- Безопасен ли pueraria lobata root extract для кожи малыша?
- Hazard and mechanism remain 'suspected' (h=2/m=2) because the extract contains phytoestrogens shown to have reproductive effects in animals and estrogenic activity in vitro. Absorption concern is increased for infants (immature skin barrier and higher surface‑area‑to‑weight); therefore exposure is increased by +1 to e=2 even though absolute dermal absorption data for the extract are limited. No infant‑specific toxicity studies were identified.
- Как VeriMom оценивает pueraria lobata root extract?
- VeriMom оценивает pueraria lobata root extract в 40/100 (средний риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы pueraria lobata root extract при беременности?
- См. наш список безопасных альтернатив pueraria lobata root extract с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.