Безопасен ли polygonum cuspidatum root extract при беременности?

Безопасные альтернативы polygonum cuspidatum root extract при беременности | VeriMom

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Безопасен ли polygonum cuspidatum root extract при беременности?

Polygonum cuspidatum root extract is a botanical source of resveratrol (and related stilbenes). Resveratrol is a phytoestrogen with demonstrated estrogen receptor agonist/partial‑agonist activity in vitro and in vivo, giving a class/mechanistic concern (m=2) but there is no EU Annex II ban or confirmed harmonised CLP H360/H350/H340 for the extract — thus hazard is scored as 1. Topical/percutaneous absorption of resveratrol is low-to-measurable, so exposure is scored 1. (Sources: PubMed reviews/studies on resveratrol ER activity; in vitro/in vivo skin permeation studies; CosIng/CIR/Cosmetic lists show extract as a cosmetic ingredient, not banned.)

Безопасен ли polygonum cuspidatum root extract при грудном вскармливании?

Same rationale as pregnancy: phytoestrogenic activity of resveratrol provides a mechanistic concern but no harmonised CMR or EU cosmetic ban; topical exposure is low but measurable. Breastfeeding-specific transfer data for topical resveratrol/extract are lacking, so exposure is treated as low (e=1).

Безопасен ли polygonum cuspidatum root extract для кожи малыша?

Hazard and mechanism same as adults (no infant‑specific evidence to change h or m). Because infants 0–3 yrs have an immature skin barrier and higher surface‑area‑to‑weight, exposure is increased by +1 (adult e=1 → infant e=2) when the ingredient/formulation allows measurable skin absorption (supported by dermal permeation studies for resveratrol).

Как VeriMom оценивает polygonum cuspidatum root extract?

VeriMom оценивает polygonum cuspidatum root extract в 60/100 (средний риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы polygonum cuspidatum root extract при беременности?

См. наш список безопасных альтернатив polygonum cuspidatum root extract с аналогичной функцией и классификацией без известных рисков.