VeriMomБезопасен ли poloxamine 504 при беременности?
No authoritative reproductive hazard classification or safety assessment (SCCS/CIR/harmonised CLP) for Poloxamine 504 was identified, and published literature on poloxamines describes them as non‑reactive block copolymer surfactants used as excipients/carrier materials rather than reproductive toxicants. Searches of PubMed found formulation and delivery studies of poloxamines but no animal or human reproductive toxicity reports. Therefore default score is 0/0/0. (See PubMed discussion of poloxamines and supplier/cosmetic ingredient listings below).
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Frequently asked questions
- Безопасен ли poloxamine 504 при беременности?
- No authoritative reproductive hazard classification or safety assessment (SCCS/CIR/harmonised CLP) for Poloxamine 504 was identified, and published literature on poloxamines describes them as non‑reactive block copolymer surfactants used as excipients/carrier materials rather than reproductive toxicants. Searches of PubMed found formulation and delivery studies of poloxamines but no animal or human reproductive toxicity reports. Therefore default score is 0/0/0. (See PubMed discussion of poloxamines and supplier/cosmetic ingredient listings below).
- Безопасен ли poloxamine 504 при грудном вскармливании?
- No evidence found that poloxamine family members (including products marketed as Poloxamine/Tetronic) cause reproductive or lactation-related toxicity or have specific milk-transfer data. No harmonised CLP (ECHA Annex VI) classification or SCCS/CIR opinion indicating developmental or lactation hazards was found. In absence of positive data, default scores are 0/0/0. Sources include formulation and biocompatibility studies and supplier/cosmetic ingredient databases.
- Безопасен ли poloxamine 504 для кожи малыша?
- No infant‑specific reproductive or developmental hazard evidence was located. Mechanistic evidence for reproductive toxicity is absent, so h/m remain 0. Exposure (e) is increased by +1 for baby skin because poloxamines are surfactant/block copolymers with some potential for dermal uptake when used topically (and infant skin has higher absorption per weight); absorption is generally low but measurable in topical formulations described in the literature, so baby_skin e=1.
- Как VeriMom оценивает poloxamine 504?
- VeriMom оценивает poloxamine 504 в 100/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы poloxamine 504 при беременности?
- См. наш список безопасных альтернатив poloxamine 504 с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.