Безопасен ли poloxamine 1302 при беременности?

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Безопасен ли poloxamine 1302 при беременности?

No harmonised CLP reproductive classification (ECHA Annex VI) or SCCS/CIR reproductive restriction identified; literature and database sources (PubChem/CosIng/ECHA C&L/ PubMed review) show no reproductive or teratogenic findings for Poloxamine-type polymers used cosmetically, so default hazard/mechanism scores are 0. Expected dermal absorption from large-block ethoxylated block copolymers is low for typical cosmetic use, supporting exposure score 0.

Безопасен ли poloxamine 1302 при грудном вскармливании?

No evidence of reproductive or lactation-specific toxicity or systemic effects in available regulatory/peer-reviewed sources; no mechanism indicating transfer in milk. Dermal systemic availability is expected to be low for this polymer class; therefore hazard and mechanism scored 0 and exposure 0.

Безопасен ли poloxamine 1302 для кожи малыша?

No infant-specific reproductive or toxicity data found. Because Poloxamine is not completely non-absorbable but generally shows low dermal absorption, infant exposure is increased by one point (e=1) to reflect higher skin permeability and surface-area-to-weight in 0–3 yr olds; hazard and mechanism remain 0 in absence of evidence of developmental/infant-specific effects.

Как VeriMom оценивает poloxamine 1302?

VeriMom оценивает poloxamine 1302 в 100/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы poloxamine 1302 при беременности?

См. наш список безопасных альтернатив poloxamine 1302 с аналогичной функцией и классификацией без известных рисков.