Безопасен ли pentasodium pentetate при беременности?
EU harmonised CLP classification lists pentasodium pentetate (CAS 140-01-2) as Reproductive toxicant Category 1B (H360D) (Commission Delegated Regulation / Annex VI update). The CIR safety assessment (2008) concluded low likelihood of dermal penetration and reported animal reproductive NOAELs, but harmonised EU classification (based on later assessment) indicates a H360-level evidence of reproductive toxicity, so hazard is scored 3. Dermal exposure from cosmetics is considered negligible based on CIR (low dermal penetration).
Безопасные альтернативы pentasodium pentetate при беременности | VeriMom
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Frequently asked questions
- Безопасен ли pentasodium pentetate при беременности?
- EU harmonised CLP classification lists pentasodium pentetate (CAS 140-01-2) as Reproductive toxicant Category 1B (H360D) (Commission Delegated Regulation / Annex VI update). The CIR safety assessment (2008) concluded low likelihood of dermal penetration and reported animal reproductive NOAELs, but harmonised EU classification (based on later assessment) indicates a H360-level evidence of reproductive toxicity, so hazard is scored 3. Dermal exposure from cosmetics is considered negligible based on CIR (low dermal penetration).
- Безопасен ли pentasodium pentetate при грудном вскармливании?
- Because pentasodium pentetate has a harmonised H360 classification (Repr. 1B), reproductive hazard is scored 3 for lactation context as well. There is no mechanistic or human lactation-specific data showing transfer into human milk, and CIR concluded likely low dermal penetration for cosmetic use, so exposure from topical cosmetics is scored 0.
- Безопасен ли pentasodium pentetate для кожи малыша?
- Hazard remains 3 because of harmonised H360 classification. Mechanistic evidence for reproductive action is not reported. CIR concluded dermal penetration is likely low but not strictly zero; per scoring rules infant exposure is increased by +1 relative to adults when measurable absorption cannot be excluded, so exposure for baby skin is scored 1.
- Как VeriMom оценивает pentasodium pentetate?
- VeriMom оценивает pentasodium pentetate в 39/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы pentasodium pentetate при беременности?
- См. наш список безопасных альтернатив pentasodium pentetate с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.