VeriMomБезопасен ли pentafluoropropane при беременности?
No harmonised CLP reproductive classification or SCCS/CIR safety assessment was found. Animal developmental studies report no teratogenic effects; a rat inhalation developmental study showed only a slight reduction in pup weight at very high exposures (50,000 ppm) but no developmental malformations, and human inhalation studies report very low systemic metabolism and low uptake (~2.1% relative uptake during exposure). Sources: Toxicol Sci (1999) developmental study; human uptake study (Toxicol Sci 2010); ECHA / EPA substance records. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/10630582/))
Pregnancy-safe products containing pentafluoropropane
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Frequently asked questions
- Безопасен ли pentafluoropropane при беременности?
- No harmonised CLP reproductive classification or SCCS/CIR safety assessment was found. Animal developmental studies report no teratogenic effects; a rat inhalation developmental study showed only a slight reduction in pup weight at very high exposures (50,000 ppm) but no developmental malformations, and human inhalation studies report very low systemic metabolism and low uptake (~2.1% relative uptake during exposure). Sources: Toxicol Sci (1999) developmental study; human uptake study (Toxicol Sci 2010); ECHA / EPA substance records. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/10630582/))
- Безопасен ли pentafluoropropane при грудном вскармливании?
- No data indicate reproductive or lactation-specific toxicity or classification. Human toxicokinetic data show minimal metabolism and rapid elimination after inhalation exposure; no data show transfer into milk. No harmonised CLP reproductive hazard. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/19915083/))
- Безопасен ли pentafluoropropane для кожи малыша?
- Pentafluoropropane (1,1,1,3,3‑pentafluoropropane, HFC‑245fa) is a volatile gas/liquid used industrially (e.g., blowing agent); there are no dermal reproductive or developmental hazard findings and dermal toxicity was not observed in available studies. Topical cosmetic use is not documented in authoritative cosmetic safety sources (no CIR or SCCS opinion or CosIng entry found), so topical exposure from cosmetics appears unlikely; available human studies address inhalation with low uptake. Therefore exposure from intended topical cosmetic use would be negligible. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/10630582/))
- Как VeriMom оценивает pentafluoropropane?
- VeriMom оценивает pentafluoropropane в 100/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы pentafluoropropane при беременности?
- См. наш список безопасных альтернатив pentafluoropropane с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.