Безопасен ли paulownia tomentosa leaf extract при беременности?
No harmonised CLP reproductive hazard (ECHA Annex VI) or SCCS/CIR safety assessment for Paulownia tomentosa leaf extract was found, and a search of PubMed yields no controlled reproductive toxicity or human teratogenicity data. Typical cosmetic topical botanical extracts have low dermal systemic bioavailability; therefore, with no evidence of reproductive hazard or known mechanism, hazard and mechanism are scored 0 and exposure 0 for pregnancy. (Sources consulted: ECHA Annex VI, SCCS/CIR absence, PubMed, CosIng, PubChem.)
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Frequently asked questions
- Безопасен ли paulownia tomentosa leaf extract при беременности?
- No harmonised CLP reproductive hazard (ECHA Annex VI) or SCCS/CIR safety assessment for Paulownia tomentosa leaf extract was found, and a search of PubMed yields no controlled reproductive toxicity or human teratogenicity data. Typical cosmetic topical botanical extracts have low dermal systemic bioavailability; therefore, with no evidence of reproductive hazard or known mechanism, hazard and mechanism are scored 0 and exposure 0 for pregnancy. (Sources consulted: ECHA Annex VI, SCCS/CIR absence, PubMed, CosIng, PubChem.)
- Безопасен ли paulownia tomentosa leaf extract при грудном вскармливании?
- No data indicating reproductive or developmental toxicity or mammary transfer; no harmonised classifications or CIR/SCCS opinions. In the absence of evidence for systemic toxicity or known mechanisms facilitating transfer into milk, hazard and mechanism are 0. Topical cosmetic use is expected to give negligible systemic exposure for adults, so exposure is scored 0. (Sources: ECHA Annex VI, PubMed, CosIng, PubChem.)
- Безопасен ли paulownia tomentosa leaf extract для кожи малыша?
- No infant-specific toxicity data or harmonised hazard classifications were found. Mechanistic evidence for reproductive or developmental activity is lacking, so h and m are 0. Because specific dermal absorption data are not available but the ingredient is a botanical extract (not inherently non-absorbable), infant skin has a higher surface-area-to-weight ratio and an immature barrier; therefore exposure is conservatively increased to 1 for 0–3 year skin. (Sources: PubMed (no infant toxicity studies), CosIng, ECHA Annex VI, PubChem.)
- Как VeriMom оценивает paulownia tomentosa leaf extract?
- VeriMom оценивает paulownia tomentosa leaf extract в 100/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы paulownia tomentosa leaf extract при беременности?
- См. наш список безопасных альтернатив paulownia tomentosa leaf extract с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.