VeriMomБезопасен ли p-cresyl isovalerate при беременности?
No EU Annex II/III listing or harmonised CLP reproductive classification found; no SCCS or CIR safety opinion specifically for p‑cresyl isovalerate. JECFA evaluated p‑cresyl isovalerate (p‑tolyl isovalerate) as a flavouring and concluded 'no safety concern at current levels of intake' (2000). ECHA substance record shows REACH registration but no harmonised reproductive hazard classification; supplier SDSs report acute oral hazard statements (H302) but not H360/H361. Given the absence of reproductive or developmental toxicity evidence, hazard (h) and mechanism (m) are scored 0; dermal absorption from a small lipophilic ester used as a fragrance is likely low but measurable, so exposure (e) = 1. Sources: ECHA substance record, JECFA, PubChem/supplier pages, EWG listing.
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Frequently asked questions
- Безопасен ли p-cresyl isovalerate при беременности?
- No EU Annex II/III listing or harmonised CLP reproductive classification found; no SCCS or CIR safety opinion specifically for p‑cresyl isovalerate. JECFA evaluated p‑cresyl isovalerate (p‑tolyl isovalerate) as a flavouring and concluded 'no safety concern at current levels of intake' (2000). ECHA substance record shows REACH registration but no harmonised reproductive hazard classification; supplier SDSs report acute oral hazard statements (H302) but not H360/H361. Given the absence of reproductive or developmental toxicity evidence, hazard (h) and mechanism (m) are scored 0; dermal absorption from a small lipophilic ester used as a fragrance is likely low but measurable, so exposure (e) = 1. Sources: ECHA substance record, JECFA, PubChem/supplier pages, EWG listing.
- Безопасен ли p-cresyl isovalerate при грудном вскармливании?
- Same evidence base as pregnancy: no harmonised CMR classification or reproductive/developmental studies for this specific compound. Dermal exposure from cosmetic use is expected to be low but measurable (fragrance ester), so exposure = 1. No data showing secretion in milk or specific lactation effects.
- Безопасен ли p-cresyl isovalerate для кожи малыша?
- No infant‑specific toxicity or developmental studies found. Following instructions to increase exposure for infants when adult absorption is measurable, exposure is increased by +1 (adult e=1 → baby e=2) because infant skin has higher surface‑area‑to‑weight and immature barrier function. Hazard and mechanism remain 0 in absence of infant‑specific evidence.
- Как VeriMom оценивает p-cresyl isovalerate?
- VeriMom оценивает p-cresyl isovalerate в 93/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы p-cresyl isovalerate при беременности?
- См. наш список безопасных альтернатив p-cresyl isovalerate с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.