VeriMomБезопасен ли n-phenyl-p-phenylenediamine при беременности?
No harmonised CLP reproductive classification or SCCS/CIR safety assessment for N‑phenyl‑p‑phenylenediamine (CAS 101‑54‑2) was identified. ECHA/REACH registration data report maternal toxicity (reduced maternal weight gain/food consumption) in dosing studies but do not report clear developmental teratogenicity; no harmonised H360/H361 classification was found. Topical/cosmetic use could give low but measurable systemic exposure. (ECHA registration dossier; ECHA substance page).
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Frequently asked questions
- Безопасен ли n-phenyl-p-phenylenediamine при беременности?
- No harmonised CLP reproductive classification or SCCS/CIR safety assessment for N‑phenyl‑p‑phenylenediamine (CAS 101‑54‑2) was identified. ECHA/REACH registration data report maternal toxicity (reduced maternal weight gain/food consumption) in dosing studies but do not report clear developmental teratogenicity; no harmonised H360/H361 classification was found. Topical/cosmetic use could give low but measurable systemic exposure. (ECHA registration dossier; ECHA substance page).
- Безопасен ли n-phenyl-p-phenylenediamine при грудном вскармливании?
- Same weight of evidence as for pregnancy: no harmonised reproductive classification or human data showing teratogenicity; REACH dossier reports maternal toxicity at high exposures but not confirmed developmental hazard. Systemic exposure from topical use is expected to be low but measurable. (ECHA registration dossier).
- Безопасен ли n-phenyl-p-phenylenediamine для кожи малыша?
- No infant‑specific reproductive or developmental hazard evidence was found. However, because baby skin has higher absorption, exposure score is increased by +1 compared with adults (adult e=1 → infant e=2). Ingredient is an aromatic amine with known skin‑sensitisation potential in the phenylenediamine family, so irritation/sensitisation risk (not scored here) is relevant for infants. (ECHA registration data; EWG entry).
- Как VeriMom оценивает n-phenyl-p-phenylenediamine?
- VeriMom оценивает n-phenyl-p-phenylenediamine в 93/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы n-phenyl-p-phenylenediamine при беременности?
- См. наш список безопасных альтернатив n-phenyl-p-phenylenediamine с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.