VeriMomБезопасен ли kaempferol rhamnoside при беременности?
No harmonised CLP reproductive classification or SCCS/CIR safety assessment was identified for kaempferol 3‑rhamnoside (Afzelin, CAS 482-39-3). ECHA substance information shows only company notifications for irritation endpoints (no H360/H361 harmonised classification). Peer‑reviewed literature for this compound reports pharmacology/toxicity studies (neuroprotective, metabolic) but no reproductive or teratology data, so there is no evidence of reproductive hazard. Low dermal/systemic absorption is expected for a polar flavonol glycoside in topical use, so exposure from normal cosmetic topical use is judged low but measurable. Sources: ECHA substance page, PubChem entry, PubMed studies.
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Frequently asked questions
- Безопасен ли kaempferol rhamnoside при беременности?
- No harmonised CLP reproductive classification or SCCS/CIR safety assessment was identified for kaempferol 3‑rhamnoside (Afzelin, CAS 482-39-3). ECHA substance information shows only company notifications for irritation endpoints (no H360/H361 harmonised classification). Peer‑reviewed literature for this compound reports pharmacology/toxicity studies (neuroprotective, metabolic) but no reproductive or teratology data, so there is no evidence of reproductive hazard. Low dermal/systemic absorption is expected for a polar flavonol glycoside in topical use, so exposure from normal cosmetic topical use is judged low but measurable. Sources: ECHA substance page, PubChem entry, PubMed studies.
- Безопасен ли kaempferol rhamnoside при грудном вскармливании?
- No data indicate reproductive or lactation-specific toxicity or endocrine disruption for afzelin. With low expected dermal absorption for the glycoside, maternal systemic exposure from cosmetic topical use would likely be low; therefore transfer to breastmilk is unlikely but not studied.
- Безопасен ли kaempferol rhamnoside для кожи малыша?
- No infant-specific safety or developmental toxicity data were found. The compound is a flavonol glycoside (polar) and not known to be a developmental toxicant; hazard is therefore scored 0. Because infant skin has an immature barrier and higher surface‑area‑to‑weight, exposure score is increased by +1 relative to adults (adult e=1 → infant e=2) to reflect higher potential per‑kg absorption if applied to baby skin.
- Как VeriMom оценивает kaempferol rhamnoside?
- VeriMom оценивает kaempferol rhamnoside в 93/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы kaempferol rhamnoside при беременности?
- См. наш список безопасных альтернатив kaempferol rhamnoside с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.