VeriMomБезопасен ли isopropyl-methylcyclohexadiene при беременности?
No harmonised reproductive classification (no H360/H361) nor CIR/SCCS harmonised opinion was found. A recent RIFM safety assessment (peer-reviewed, PubMed) for (−)-(R)-α‑phellandrene (CAS 4221-98-1) reports a large margin of exposure for repeated‑dose endpoints and calculates very low systemic exposure from typical topical use, supporting no evidence of reproductive hazard; therefore hazard and mechanism scores default to 0. Measurable systemic exposure was estimated in the RIFM assessment (used to calculate MOE), so exposure is scored as low but measurable (1). (Sources: RIFM/PubMed; ECHA substance info; manufacturer SDS).
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Frequently asked questions
- Безопасен ли isopropyl-methylcyclohexadiene при беременности?
- No harmonised reproductive classification (no H360/H361) nor CIR/SCCS harmonised opinion was found. A recent RIFM safety assessment (peer-reviewed, PubMed) for (−)-(R)-α‑phellandrene (CAS 4221-98-1) reports a large margin of exposure for repeated‑dose endpoints and calculates very low systemic exposure from typical topical use, supporting no evidence of reproductive hazard; therefore hazard and mechanism scores default to 0. Measurable systemic exposure was estimated in the RIFM assessment (used to calculate MOE), so exposure is scored as low but measurable (1). (Sources: RIFM/PubMed; ECHA substance info; manufacturer SDS).
- Безопасен ли isopropyl-methylcyclohexadiene при грудном вскармливании?
- No data indicating developmental/reproductive toxicity, no harmonised CLP reproductive flags, and no evidence of mammary transfer or lactation-specific toxicity was identified. Given the compound is a lipophilic monoterpene with low but measurable systemic exposure after topical use (RIFM assessment), exposure for breastfeeding is scored as low but measurable (1).
- Безопасен ли isopropyl-methylcyclohexadiene для кожи малыша?
- No infant‑specific toxicity or developmental data were found that would increase hazard or mechanism scores. Because alpha‑phellandrene is lipophilic and the RIFM assessment estimates measurable systemic exposure in adults, the exposure score for baby skin is increased by +1 (per your rules) to 2 to reflect immature barrier and higher surface‑area‑to‑weight in 0–3‑year‑olds. Note: the substance is noted in SDSs as a skin sensitiser (Skin Sens. 1B in supplier/MSDS documents), so avoid use on infants if there's potential for sensitisation.
- Как VeriMom оценивает isopropyl-methylcyclohexadiene?
- VeriMom оценивает isopropyl-methylcyclohexadiene в 93/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы isopropyl-methylcyclohexadiene при беременности?
- См. наш список безопасных альтернатив isopropyl-methylcyclohexadiene с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.