Безопасен ли isocetyl salicylate при беременности?

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Безопасен ли isocetyl salicylate при беременности?

No EU Annex II/III listing or harmonised CLP CMR classification was found, and the Cosmetic Ingredient Review (CIR) includes isocetyl salicylate within its salicylates safety assessment without identifying reproductive/teratogenic hazards. No animal reproductive or human teratogenic studies specific to isocetyl salicylate were located. Given its very high estimated logP and low water solubility, topical systemic absorption is expected to be low but measurable, so exposure is scored as low (e=1). (Sources: CIR salicylates assessment; CIR ingredient page; PubChem; SpecialChem).

Безопасен ли isocetyl salicylate при грудном вскармливании?

No evidence of reproductive or lactation-specific toxicity or harmonised classifications for isocetyl salicylate was found. Because systemic exposure from typical topical use is expected to be low but measurable, a low exposure score (e=1) is used for breastfeeding. No mechanistic evidence of placental or milk transfer for this specific ester was identified.

Безопасен ли isocetyl salicylate для кожи малыша?

No infant-specific hazard or mechanistic data were found. Per your instructions, infant exposure scoring is increased by +1 relative to adults because infant skin is more permeable and the compound has measurable (low) dermal absorption; therefore exposure for baby skin is scored as moderate (e=2). No direct infant dermal toxicity or developmental effects were identified in the literature reviewed.

Как VeriMom оценивает isocetyl salicylate?

VeriMom оценивает isocetyl salicylate в 93/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы isocetyl salicylate при беременности?

См. наш список безопасных альтернатив isocetyl salicylate с аналогичной функцией и классификацией без известных рисков.