Безопасен ли isobutyl methylaminobenzoate при беременности?
No harmonised CLP reproductive classification or SCCS/CIR adverse pregnancy finding was identified. A peer‑reviewed RIFM (fragrance) safety assessment (Food Chem Toxicol, 2017) evaluated isobutyl N‑methylanthranilate (CAS 65505‑24‑0) without identifying reproductive/teratogenic hazards; it is used at low levels in flavours/fragrances and IFRA/FEMA/JECFA list it for uses with limits, supporting low consumer exposure. Physicochemical data (logP ~3.6) indicate some potential for dermal uptake but typical cosmetic concentrations and IFRA limits make systemic exposure low but measurable, so e=1 (low but measurable).
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Frequently asked questions
- Безопасен ли isobutyl methylaminobenzoate при беременности?
- No harmonised CLP reproductive classification or SCCS/CIR adverse pregnancy finding was identified. A peer‑reviewed RIFM (fragrance) safety assessment (Food Chem Toxicol, 2017) evaluated isobutyl N‑methylanthranilate (CAS 65505‑24‑0) without identifying reproductive/teratogenic hazards; it is used at low levels in flavours/fragrances and IFRA/FEMA/JECFA list it for uses with limits, supporting low consumer exposure. Physicochemical data (logP ~3.6) indicate some potential for dermal uptake but typical cosmetic concentrations and IFRA limits make systemic exposure low but measurable, so e=1 (low but measurable).
- Безопасен ли isobutyl methylaminobenzoate при грудном вскармливании?
- No data were found showing transfer into milk or lactation toxicity; no regulatory reproductive hazard flags. Given low systemic exposure from topical use (see RIFM assessment and IFRA limits), breastfeeding exposure is expected to be low but measurable.
- Безопасен ли isobutyl methylaminobenzoate для кожи малыша?
- No infant‑specific reproductive or developmental toxicity data were identified. Following your scoring rules, adult exposure judged low (e=1) is increased by +1 for infants because of immature barrier/higher surface‑area‑to‑weight, giving e=2. No evidence supports raising hazard (h) or mechanism (m) for infants.
- Как VeriMom оценивает isobutyl methylaminobenzoate?
- VeriMom оценивает isobutyl methylaminobenzoate в 93/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы isobutyl methylaminobenzoate при беременности?
- См. наш список безопасных альтернатив isobutyl methylaminobenzoate с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.