VeriMomБезопасен ли isobavachalcone при беременности?
No harmonised CLP classification (ECHA Annex VI), no SCCS or CIR safety assessment found, and no reliable animal or human reproductive toxicity data located in PubMed or ECHA registration dossiers for isobavachalcone (CAS 20784-50-3). Therefore there is no evidence of reproductive hazard. Limited physicochemical and in vitro literature (PubMed/PubChem) indicates biological activity of isobavachalcone (e.g., antimicrobial/anticancer in vitro), but no pregnancy-specific toxicology; topical cosmetic exposure is plausibly low but measurable due to its lipophilic small-molecule nature (hence e=1).
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Frequently asked questions
- Безопасен ли isobavachalcone при беременности?
- No harmonised CLP classification (ECHA Annex VI), no SCCS or CIR safety assessment found, and no reliable animal or human reproductive toxicity data located in PubMed or ECHA registration dossiers for isobavachalcone (CAS 20784-50-3). Therefore there is no evidence of reproductive hazard. Limited physicochemical and in vitro literature (PubMed/PubChem) indicates biological activity of isobavachalcone (e.g., antimicrobial/anticancer in vitro), but no pregnancy-specific toxicology; topical cosmetic exposure is plausibly low but measurable due to its lipophilic small-molecule nature (hence e=1).
- Безопасен ли isobavachalcone при грудном вскармливании?
- There are no authoritative assessments (CIR/SCCS) or animal/human lactation studies identified indicating risk from isobavachalcone. Because systemic absorption after topical use is plausible but expected to be low, low but measurable exposure to breastfed infants via milk cannot be excluded (e=1).
- Безопасен ли isobavachalcone для кожи малыша?
- No infant-specific toxicity or dermal reproductive/developmental data were located. Given measurable dermal absorption in adults is plausible, infant exposure via topical application to 0–3 yr skin is increased due to immature barrier and higher surface-area-to-weight; exposure score increased by +1 relative to adult (adult e=1 → baby e=2). No evidence supports increasing hazard or mechanism scores for infants.
- Как VeriMom оценивает isobavachalcone?
- VeriMom оценивает isobavachalcone в 93/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы isobavachalcone при беременности?
- См. наш список безопасных альтернатив isobavachalcone с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.