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Безопасен ли hydroxyisohexyl 3-cyclohexene carboxaldehyde при беременности?

No harmonised CLP reproductive classification (H360/H361) for hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC / Lyral) was identified in the authoritative ECHA/C&L materials; the regulatory and expert literature and safety reviews focus on skin sensitisation rather than reproductive toxicity. Systemic exposure from normal cosmetic topical use is low but measurable, so exposure during pregnancy is scored as low (e=1). Sources: SCCS opinion on HICC (sensitisation focus) and ECHA notices/public consultation (no confirmed harmonised repro classification). (https://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_q_022.pdf; https://echa.europa.eu/all-news/-/journal_content/56d34d61-2a1f-4f23-a3d6-0f4f5a5a0b9a).

Ингредиенты
hydroxyisohexyl 3-cyclohexene carboxaldehyde
СРЕДНИЙ РИСК
53
/100
0

Безопасные альтернативы hydroxyisohexyl 3-cyclohexene carboxaldehyde при беременности | VeriMom

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Frequently asked questions

Безопасен ли hydroxyisohexyl 3-cyclohexene carboxaldehyde при беременности?
No harmonised CLP reproductive classification (H360/H361) for hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC / Lyral) was identified in the authoritative ECHA/C&L materials; the regulatory and expert literature and safety reviews focus on skin sensitisation rather than reproductive toxicity. Systemic exposure from normal cosmetic topical use is low but measurable, so exposure during pregnancy is scored as low (e=1). Sources: SCCS opinion on HICC (sensitisation focus) and ECHA notices/public consultation (no confirmed harmonised repro classification). (https://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_q_022.pdf; https://echa.europa.eu/all-news/-/journal_content/56d34d61-2a1f-4f23-a3d6-0f4f5a5a0b9a).
Безопасен ли hydroxyisohexyl 3-cyclohexene carboxaldehyde при грудном вскармливании?
There is no credible evidence in authoritative safety reviews or peer‑reviewed studies that HICC is a reproductive or lactation hazard or that it concentrates in milk; therefore hazard (h) and mechanism (m) are scored 0. Because topical use can produce low but measurable systemic absorption in adults, breastfeeding exposure is scored low (e=1). Sources: RIFM/Cosmetic safety reviews and PubChem summary; no studies showing transfer to milk or developmental effects were located. (https://pubmed.ncbi.nlm.nih.gov/35605712/; https://pubchem.ncbi.nlm.nih.gov/compound/Hydroxyisohexyl-3-cyclohexene-carboxaldehyde).
Безопасен ли hydroxyisohexyl 3-cyclohexene carboxaldehyde для кожи малыша?
No infant‑specific data showing reproductive or developmental toxicity; primary, high‑priority sources (SCCS, RIFM reviews, peer‑reviewed literature) identify HICC chiefly as a contact allergen (skin sensitiser), not a developmental toxicant. Because infant skin (0–3 yr) has higher absorption per body weight and an immature barrier, exposure score is increased by +1 relative to adults (adult e=1 → baby e=2). Note: this scoring does not change the hazard (h) or mechanism (m) in the absence of infant‑specific evidence. (SCCS opinion and multiple patch‑test / contact dermatitis studies). (https://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_q_022.pdf; https://pubmed.ncbi.nlm.nih.gov/27767215/; https://pubmed.ncbi.nlm.nih.gov/23869726/).
Как VeriMom оценивает hydroxyisohexyl 3-cyclohexene carboxaldehyde?
VeriMom оценивает hydroxyisohexyl 3-cyclohexene carboxaldehyde в 53/100 (средний риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
Какие безопасные альтернативы hydroxyisohexyl 3-cyclohexene carboxaldehyde при беременности?
См. наш список безопасных альтернатив hydroxyisohexyl 3-cyclohexene carboxaldehyde с аналогичной функцией и классификацией без известных рисков.

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Медицинская оговорка

Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.

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