Безопасен ли hydroxyacetophenone при беременности?
CIR’s safety assessment (Cosmetic Ingredient Review, 2022 draft/final) concluded hydroxyacetophenone (p‑hydroxyacetophenone; CAS 99‑93‑4) is safe as used in cosmetics and found no reproductive/developmental hazard at use‑relevant exposures (NOAELs in animal studies reported but no reproductive signal at cosmetic exposures). No harmonised CLP reproductive classifications (H360/H361) were found on ECHA; company CLP notifications list general irritation/acute hazards but not reproductive classification. ([cir-safety.org](https://cir-safety.org/sites/default/files/Hydroxyacetophenone.pdf))
Pregnancy-safe products containing hydroxyacetophenone










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Frequently asked questions
- Безопасен ли hydroxyacetophenone при беременности?
- CIR’s safety assessment (Cosmetic Ingredient Review, 2022 draft/final) concluded hydroxyacetophenone (p‑hydroxyacetophenone; CAS 99‑93‑4) is safe as used in cosmetics and found no reproductive/developmental hazard at use‑relevant exposures (NOAELs in animal studies reported but no reproductive signal at cosmetic exposures). No harmonised CLP reproductive classifications (H360/H361) were found on ECHA; company CLP notifications list general irritation/acute hazards but not reproductive classification. ([cir-safety.org](https://cir-safety.org/sites/default/files/Hydroxyacetophenone.pdf))
- Безопасен ли hydroxyacetophenone при грудном вскармливании?
- There are no authoritative safety assessments (CIR/SCCS/harmonised CLP) indicating reproductive/lactation hazards or breast‑milk transfer for hydroxyacetophenone; available toxicology (CIR review, ECHA dossiers, and literature) does not identify specific lactation/breastfeeding risks at cosmetic use levels. No peer‑reviewed human lactation studies were identified. ([cir-safety.org](https://cir-safety.org/sites/default/files/Hydroxyacetophenone.pdf))
- Безопасен ли hydroxyacetophenone для кожи малыша?
- Hazard and mechanism remain not indicated by CIR/ECHA (h=0,m=0). Adult exposure was judged negligible for reproductive hazard in authoritative reviews; however, infant skin has a higher surface‑area:weight ratio and an immature barrier, so exposure scoring for baby skin is increased by +1 per your rules (adult e=0 → baby e=1) in absence of data proving zero dermal absorption. CIR found no reproductive concerns and performed dermal irritation/sensitization assessments but did not provide human dermal‑absorption data sufficient to demonstrate zero absorption. ([cir-safety.org](https://cir-safety.org/sites/default/files/Hydroxyacetophenone.pdf))
- Как VeriMom оценивает hydroxyacetophenone?
- VeriMom оценивает hydroxyacetophenone в 100/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы hydroxyacetophenone при беременности?
- См. наш список безопасных альтернатив hydroxyacetophenone с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.