Безопасен ли humulus lupulus extract при беременности?

Безопасные альтернативы humulus lupulus extract при беременности | VeriMom

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Безопасен ли humulus lupulus extract при беременности?

Humulus lupulus (hops) extracts contain prenylflavonoids (notably 8‑prenylnaringenin, 8‑PN) with demonstrated estrogenic activity in vitro and in animal models; this supports a class-based reproductive concern but there is no EU Annex II/III restriction or harmonised reproductive classification. (CIR safety review; identification of 8‑PN).

Безопасен ли humulus lupulus extract при грудном вскармливании?

Same mechanistic concern (phytoestrogenic constituents such as 8‑PN) applies; however, there is no evidence of harmonised classification or explicit contraindication for topical cosmetic use during lactation. Systemic transfer via breastmilk is theoretically possible if maternal systemic exposure is significant, but typical topical cosmetic exposure is low. (CIR; animal/human data on hop prenylflavonoids).

Безопасен ли humulus lupulus extract для кожи малыша?

Hazard and mechanism mirror adult concerns (presence of estrogenic prenylflavonoids). Exposure score for infants increased because immature skin barrier and higher surface-area-to-weight make percutaneous absorption more likely even when adult topical absorption is low; no infant‑specific adverse data were located. (CIR; PubMed reviews on hop prenylflavonoids).

Как VeriMom оценивает humulus lupulus extract?

VeriMom оценивает humulus lupulus extract в 60/100 (средний риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы humulus lupulus extract при беременности?

См. наш список безопасных альтернатив humulus lupulus extract с аналогичной функцией и классификацией без известных рисков.