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Безопасен ли hc red no. 21 при беременности?

HC Red No. 21 is reported in regulatory/cosmetic databases as 5‑amino‑4‑chloro‑o‑cresol (and its HCl salt) used as a hair dye intermediate. The Cosmetic Ingredient Review (CIR) reviewed 5‑amino‑4‑chloro‑o‑cresol and found data gaps but did not identify a harmonised reproductive classification or conclusive reproductive hazard; therefore default hazard is 0. Dermal/topical use of hair dye intermediates can result in low but measurable exposure, so exposure (e) is set to 1. ([cir-safety.org](https://www.cir-safety.org/sites/default/files/5-Amino-4-Chloro-o-Cresol.pdf?utm_source=openai))

Ингредиенты
hc red no. 21
БЕЗ ИЗВЕСТНЫХ РИСКОВ
93
/100
0

Related ingredients

Frequently asked questions

Безопасен ли hc red no. 21 при беременности?
HC Red No. 21 is reported in regulatory/cosmetic databases as 5‑amino‑4‑chloro‑o‑cresol (and its HCl salt) used as a hair dye intermediate. The Cosmetic Ingredient Review (CIR) reviewed 5‑amino‑4‑chloro‑o‑cresol and found data gaps but did not identify a harmonised reproductive classification or conclusive reproductive hazard; therefore default hazard is 0. Dermal/topical use of hair dye intermediates can result in low but measurable exposure, so exposure (e) is set to 1. ([cir-safety.org](https://www.cir-safety.org/sites/default/files/5-Amino-4-Chloro-o-Cresol.pdf?utm_source=openai))
Безопасен ли hc red no. 21 при грудном вскармливании?
No harmonised CLP reproductive/teratogenic classification (H360/H361) nor clinical human reproductive/breastfeeding hazards were identified in the major authoritative sources searched. Mechanistic evidence for transfer into breastmilk or specific lactation toxicity was not found. Topical use implies low but measurable systemic exposure, so exposure=1. ([cir-safety.org](https://www.cir-safety.org/sites/default/files/5-Amino-4-Chloro-o-Cresol.pdf?utm_source=openai))
Безопасен ли hc red no. 21 для кожи малыша?
There is no authoritative evidence (harmonised CLP, SCCS/CIR conclusion of reproductive hazard, or peer‑reviewed data) that 5‑amino‑4‑chloro‑o‑cresol is a reproductive or developmental toxicant; hazard and mechanism remain 0. Because infant skin (0–3 yr) has higher surface‑area‑to‑weight and an immature barrier and the compound shows some potential for percutaneous uptake in topical contexts, exposure for baby skin is increased by +1 relative to adult topical use (adult e=1 → baby e=2). No infant‑specific adverse data were located. ([cir-safety.org](https://www.cir-safety.org/sites/default/files/5-Amino-4-Chloro-o-Cresol.pdf?utm_source=openai))
Как VeriMom оценивает hc red no. 21?
VeriMom оценивает hc red no. 21 в 93/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.
Какие безопасные альтернативы hc red no. 21 при беременности?
См. наш список безопасных альтернатив hc red no. 21 с аналогичной функцией и классификацией без известных рисков.

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Медицинская оговорка

Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.

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