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Безопасен ли glycyrrhiza glabra root water при беременности?

No EU Annex II/III restriction or harmonised CLP reproductive classification was identified; the Cosmetic Ingredient Review (CIR) concluded Glycyrrhiza-derived cosmetic ingredients are safe for topical use as used. However, peer‑reviewed human and animal literature links maternal licorice/glycyrrhizin exposure to reproductive/developmental outcomes (preterm delivery, altered child neuroendocrine/cognitive outcomes) via demonstrated inhibition of placental 11β‑HSD2, so a class/mechanistic concern exists though primarily for oral/high exposures and not supported by an EU harmonised hazard classification. Sources: CIR/CosmeticsInfo; PubMed epidemiology/mechanistic studies.

Ингредиенты
glycyrrhiza glabra root water
СРЕДНИЙ РИСК
60
/100
0

Pregnancy-safe products containing glycyrrhiza glabra root water

Безопасные альтернативы glycyrrhiza glabra root water при беременности | VeriMom

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Frequently asked questions

Безопасен ли glycyrrhiza glabra root water при беременности?
No EU Annex II/III restriction or harmonised CLP reproductive classification was identified; the Cosmetic Ingredient Review (CIR) concluded Glycyrrhiza-derived cosmetic ingredients are safe for topical use as used. However, peer‑reviewed human and animal literature links maternal licorice/glycyrrhizin exposure to reproductive/developmental outcomes (preterm delivery, altered child neuroendocrine/cognitive outcomes) via demonstrated inhibition of placental 11β‑HSD2, so a class/mechanistic concern exists though primarily for oral/high exposures and not supported by an EU harmonised hazard classification. Sources: CIR/CosmeticsInfo; PubMed epidemiology/mechanistic studies.
Безопасен ли glycyrrhiza glabra root water при грудном вскармливании?
Same rationale as pregnancy: no regulatory ban or harmonised CMR classification, CIR finds topical licorice ingredients safe as used, but glycyrrhizin/glycyrrhetinic acid have demonstrated endocrine activity (placental 11β‑HSD2 inhibition) and systemic effects after ingestion; breastfeeding concerns are theoretical at topical cosmetic exposures but mechanism is demonstrated for systemic exposures.
Безопасен ли glycyrrhiza glabra root water для кожи малыша?
Hazard and mechanism scores are unchanged (no infant‑specific hazard data), but exposure (e) is increased by +1 for infants because immature skin barrier and higher surface‑area‑to‑weight can raise absorption; no evidence found that topical cosmetic use of Glycyrrhiza glabra root water is specifically harmful to infant skin, and CIR concluded dermal penetration is low for typical cosmetic preparations.
Как VeriMom оценивает glycyrrhiza glabra root water?
VeriMom оценивает glycyrrhiza glabra root water в 60/100 (средний риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
Какие безопасные альтернативы glycyrrhiza glabra root water при беременности?
См. наш список безопасных альтернатив glycyrrhiza glabra root water с аналогичной функцией и классификацией без известных рисков.

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Медицинская оговорка

Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.

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