VeriMomБезопасен ли fisetin при беременности?
No harmonised CLP (ECHA Annex VI) or SCCS/CIR reproductive/teratogenic classification for fisetin was identified in the authoritative sources searched; peer‑reviewed animal studies did not report teratogenicity and in some pregnancy models fisetin was protective (e.g., preeclampsia‑like rat model and mitigation of methylmercury developmental neurotoxicity). Some in vitro and in vivo work shows interaction with estrogen and androgen signalling (ER/AR modulation), but there is no evidence of a reproductive mechanism causing human/animal developmental toxicity. Given its molecular size and physicochemistry there is potential for low but measurable dermal absorption from topical use. Sources: PubMed studies and ECHA/C&L/SDS listings (self‑notifications exist in some supplier SDSs but these are not harmonised CLH and per your instruction do not raise hazard score).
Pregnancy-safe products containing fisetin
Related ingredients
Frequently asked questions
- Безопасен ли fisetin при беременности?
- No harmonised CLP (ECHA Annex VI) or SCCS/CIR reproductive/teratogenic classification for fisetin was identified in the authoritative sources searched; peer‑reviewed animal studies did not report teratogenicity and in some pregnancy models fisetin was protective (e.g., preeclampsia‑like rat model and mitigation of methylmercury developmental neurotoxicity). Some in vitro and in vivo work shows interaction with estrogen and androgen signalling (ER/AR modulation), but there is no evidence of a reproductive mechanism causing human/animal developmental toxicity. Given its molecular size and physicochemistry there is potential for low but measurable dermal absorption from topical use. Sources: PubMed studies and ECHA/C&L/SDS listings (self‑notifications exist in some supplier SDSs but these are not harmonised CLH and per your instruction do not raise hazard score).
- Безопасен ли fisetin при грудном вскармливании?
- No authoritative safety assessment (CIR or SCCS) or harmonised classification indicating harm to breastfed children was found. No controlled human data showing transfer into milk or adverse effects in suckling offspring; some animal pregnancy studies showed protective effects rather than toxicity. Dermal exposure from cosmetics would be expected to give low but measurable systemic exposure in adults, so a low exposure score is used. Self‑classified SDS statements claiming reproductive/breastfeeding hazard are present for some supplier documents but are not equivalent to harmonised CLH and were not used to increase the hazard score.
- Безопасен ли fisetin для кожи малыша?
- No infant‑specific hazard evidence was identified. Per the scoring rules, because fisetin shows measurable dermal absorption in principle (small flavonol) the exposure score for baby skin is increased by +1 relative to adults to account for immature barrier and higher surface‑area‑to‑weight; there is no direct data showing increased hazard or infant‑specific mechanism, so hazard and mechanism scores remain at default.
- Как VeriMom оценивает fisetin?
- VeriMom оценивает fisetin в 93/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы fisetin при беременности?
- См. наш список безопасных альтернатив fisetin с аналогичной функцией и классификацией без известных рисков.
Проверь любой состав за 2 секунды
Скачай VeriMom бесплатно — отсканируй любой продукт и мгновенно получи оценку безопасности при беременности.
Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.