Безопасен ли dihydro-alpha-terpinol при беременности?
No harmonised CLP reproductive classification found and authoritative fragrance safety review (RIFM; peer‑reviewed Food and Chemical Toxicology assessment) concluded there are insufficient direct toxicity data for CAS 498-81-7 but read-across to a structural analogue did not indicate reproductive/developmental concern. ECHA registration dossiers for related terpineol materials report reproductive findings only at very high systemic doses for alpha‑terpineol; these are read‑across / high‑dose gavage effects and not harmonised classifications. Given the lack of adverse reproductive evidence for dihydro-α-terpineol, hazard is scored 0; mechanism 0. Moderate lipophilicity (log Kow ~3.1–3.4) supports low but measurable dermal absorption for typical cosmetic use → exposure = 1. (Sources: RIFM safety assessment; ECHA registration summaries.)
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Frequently asked questions
- Безопасен ли dihydro-alpha-terpinol при беременности?
- No harmonised CLP reproductive classification found and authoritative fragrance safety review (RIFM; peer‑reviewed Food and Chemical Toxicology assessment) concluded there are insufficient direct toxicity data for CAS 498-81-7 but read-across to a structural analogue did not indicate reproductive/developmental concern. ECHA registration dossiers for related terpineol materials report reproductive findings only at very high systemic doses for alpha‑terpineol; these are read‑across / high‑dose gavage effects and not harmonised classifications. Given the lack of adverse reproductive evidence for dihydro-α-terpineol, hazard is scored 0; mechanism 0. Moderate lipophilicity (log Kow ~3.1–3.4) supports low but measurable dermal absorption for typical cosmetic use → exposure = 1. (Sources: RIFM safety assessment; ECHA registration summaries.)
- Безопасен ли dihydro-alpha-terpinol при грудном вскармливании?
- Same rationale as pregnancy: no harmonised reproductive classification or authoritative body (CIR/SCCS/Harmonised CLP) flagging lactation transfer or breastmilk concerns for this substance. Read‑across data do not indicate lactation-specific hazards. Dermal use implies low but measurable systemic exposure in adults → exposure = 1.
- Безопасен ли dihydro-alpha-terpinol для кожи малыша?
- No infant-specific hazard data were identified. Per your instructions, because adult topical exposure is assessed as low but measurable (e=1) and infants (0–3 yr) have higher skin permeability and surface-area-to-weight, exposure is increased by +1 (to e=2). There is no direct evidence to increase hazard or mechanism scores for infants.
- Как VeriMom оценивает dihydro-alpha-terpinol?
- VeriMom оценивает dihydro-alpha-terpinol в 93/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы dihydro-alpha-terpinol при беременности?
- См. наш список безопасных альтернатив dihydro-alpha-terpinol с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.