Безопасен ли dibutyl maleate при беременности?

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Frequently asked questions

Безопасен ли dibutyl maleate при беременности?

No harmonised CLP reproductive classification for dibutyl maleate and available registration/REACH screening data (OECD TG 421/422-type reproductive/developmental screening tests reported in dossiers) did not identify reproductive or developmental effects; therefore hazard and mechanism are scored 0. Dermal absorption is plausible for a lipophilic ester used in formulations so exposure from topical cosmetic use is scored low (e=1). Sources: ECHA registration dossier and OECD-type screening studies; PubChem; EWG. ([echa.europa.eu](https://www.echa.europa.eu/substance-information/-/substanceinfo/100.000.980?utm_source=openai))

Безопасен ли dibutyl maleate при грудном вскармливании?

Same rationale as pregnancy: no evidence of reproductive/developmental hazard or mechanistic data indicating transfer via milk; topical cosmetic use gives low but measurable exposure (e=1). ([echa.europa.eu](https://www.echa.europa.eu/substance-information/-/substanceinfo/100.000.980?utm_source=openai))

Безопасен ли dibutyl maleate для кожи малыша?

No infant-specific hazard or mechanistic data were identified, so h and m remain 0. Per your rules, exposure (e) is increased by +1 for baby skin because dibutyl maleate has measurable dermal absorption in adults (lipophilic ester) and infant skin has higher uptake — giving e=2. ([pubchem.ncbi.nlm.nih.gov](https://pubchem.ncbi.nlm.nih.gov/compound/Dibutyl-maleate))

Как VeriMom оценивает dibutyl maleate?

VeriMom оценивает dibutyl maleate в 93/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы dibutyl maleate при беременности?

См. наш список безопасных альтернатив dibutyl maleate с аналогичной функцией и классификацией без известных рисков.