VeriMomБезопасен ли crotonaldehyde при беременности?
Crotonaldehyde has a harmonised CLP classification for germ‑cell mutagenicity (Muta.2 H341) but not for reproductive toxicity (no H360/H361 harmonised classification). Regulatory and review sources (ECHA/Annex VI, IARC, EPA/ORNL) and the literature review report no mammalian developmental/reproductive studies located; therefore there is no basis to assign a reproductive hazard (h=0). Mechanistic reproductive pathways are not established (m=0). Dermal exposure from cosmetic use is plausible/measurable (e=1) because crotonaldehyde is a small reactive aldehyde with recognised skin/respiratory hazards; however specific cosmetic dermal absorption data are lacking, so exposure is scored as low but measurable. Sources: ECHA Annex VI classification summary; IARC Monograph 128; EPA/ORNL issue paper; EWG entry.
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Frequently asked questions
- Безопасен ли crotonaldehyde при беременности?
- Crotonaldehyde has a harmonised CLP classification for germ‑cell mutagenicity (Muta.2 H341) but not for reproductive toxicity (no H360/H361 harmonised classification). Regulatory and review sources (ECHA/Annex VI, IARC, EPA/ORNL) and the literature review report no mammalian developmental/reproductive studies located; therefore there is no basis to assign a reproductive hazard (h=0). Mechanistic reproductive pathways are not established (m=0). Dermal exposure from cosmetic use is plausible/measurable (e=1) because crotonaldehyde is a small reactive aldehyde with recognised skin/respiratory hazards; however specific cosmetic dermal absorption data are lacking, so exposure is scored as low but measurable. Sources: ECHA Annex VI classification summary; IARC Monograph 128; EPA/ORNL issue paper; EWG entry.
- Безопасен ли crotonaldehyde при грудном вскармливании?
- Same rationale as for pregnancy: no harmonised reproductive classification (H360/H361) or mammalian reproductive/developmental data located to justify reproductive hazard. No data showing transfer into breastmilk; dermal/topical exposure is plausibly low‑but‑measurable (e=1).
- Безопасен ли crotonaldehyde для кожи малыша?
- No infant‑specific reproductive or mechanistic evidence was found, so h and m remain 0. Because baby skin has higher absorption per weight and the adult exposure was scored as measurable (e=1), the exposure score is increased by +1 for babies (e=2). There are no infant dermal absorption studies for crotonaldehyde in cosmetics.
- Как VeriMom оценивает crotonaldehyde?
- VeriMom оценивает crotonaldehyde в 93/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы crotonaldehyde при беременности?
- См. наш список безопасных альтернатив crotonaldehyde с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.