VeriMomБезопасен ли crocus sativus flower extract при беременности?
Animal and preclinical studies report effects on pregnancy/reproductive hormones and fetal outcomes after oral administration of Crocus sativus / saffron extracts or constituents (crocin, safranal), so reproductive hazard is suspected (animal evidence). No EU Annex II/III listing or harmonised CLP CMR classification was found, so the suspicion is based on in vivo studies rather than regulatory classification. (See PubMed studies and reviews reporting fetal resorption, hormone changes, and uterine-stimulant/abortifacient effects after oral/high doses). ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/24097366/?utm_source=openai))
Безопасные альтернативы crocus sativus flower extract при беременности | VeriMom
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Frequently asked questions
- Безопасен ли crocus sativus flower extract при беременности?
- Animal and preclinical studies report effects on pregnancy/reproductive hormones and fetal outcomes after oral administration of Crocus sativus / saffron extracts or constituents (crocin, safranal), so reproductive hazard is suspected (animal evidence). No EU Annex II/III listing or harmonised CLP CMR classification was found, so the suspicion is based on in vivo studies rather than regulatory classification. (See PubMed studies and reviews reporting fetal resorption, hormone changes, and uterine-stimulant/abortifacient effects after oral/high doses). ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/24097366/?utm_source=openai))
- Безопасен ли crocus sativus flower extract при грудном вскармливании?
- No direct human breastfeeding transfer studies for cosmetic topical use were found. Because the ingredient contains bioactive constituents with evidence of systemic activity after oral dosing in animals/humans, a low-level concern exists by analogy (theoretical/mechanistic) but no direct evidence of harm from topical cosmetic use or of transfer in human milk was identified. Regulatory sources do not list bans/restrictions. ([pmc.ncbi.nlm.nih.gov](https://pmc.ncbi.nlm.nih.gov/articles/PMC8860555/?utm_source=openai))
- Безопасен ли crocus sativus flower extract для кожи малыша?
- Hazard and mechanism mirror the pregnancy assessment (animal reproductive effects and hormone-altering activity). Exposure (e) is increased for baby skin (+1) because infant skin has higher absorption per weight and the extract contains bioactive small molecules (crocin/crocetin/safranal) that have measurable systemic activity when absorbed; however, no infant-specific studies were found. No regulatory ban/restriction for cosmetic topical use was identified. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/24097366/?utm_source=openai))
- Как VeriMom оценивает crocus sativus flower extract?
- VeriMom оценивает crocus sativus flower extract в 40/100 (средний риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы crocus sativus flower extract при беременности?
- См. наш список безопасных альтернатив crocus sativus flower extract с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.