VeriMomБезопасен ли coptis japonica rhizome extract при беременности?
Coptis japonica rhizome extract (CAS 223748-66-1) is listed in the EU cosmetic ingredients list (Cosmetic Directive publication) as a permitted botanical extract with no Annex II ban or Annex III restriction; no harmonised CLP reproductive (H360/H361) or CMR classification was found. Large epidemiology on related Coptis/Coptidis rhizoma used orally showed no clear adverse effect on fetal growth at usual use, and mutagenicity testing of Coptis rhizome extracts did not indicate strong genotoxicity across standard assays. Given lack of reproductive/teratogenic animal or harmonised hazard data, hazard (h) and mechanism (m) are scored 0. Topical exposure is scored as low but measurable (e=1) because botanical extracts can deliver small amounts of phytochemicals through skin but no specific dermal absorption data were found.
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Frequently asked questions
- Безопасен ли coptis japonica rhizome extract при беременности?
- Coptis japonica rhizome extract (CAS 223748-66-1) is listed in the EU cosmetic ingredients list (Cosmetic Directive publication) as a permitted botanical extract with no Annex II ban or Annex III restriction; no harmonised CLP reproductive (H360/H361) or CMR classification was found. Large epidemiology on related Coptis/Coptidis rhizoma used orally showed no clear adverse effect on fetal growth at usual use, and mutagenicity testing of Coptis rhizome extracts did not indicate strong genotoxicity across standard assays. Given lack of reproductive/teratogenic animal or harmonised hazard data, hazard (h) and mechanism (m) are scored 0. Topical exposure is scored as low but measurable (e=1) because botanical extracts can deliver small amounts of phytochemicals through skin but no specific dermal absorption data were found.
- Безопасен ли coptis japonica rhizome extract при грудном вскармливании?
- No evidence of a reproductive or lactation hazard, no harmonised classifications, and no human data showing transfer via breastmilk for cosmetic topical use. Exposure considered low but measurable (e=1) for adult topical use in absence of dermal absorption data.
- Безопасен ли coptis japonica rhizome extract для кожи малыша?
- No infant-specific toxicity or developmental hazards were identified. Per scoring rules, exposure for 0–3 yr skin is increased by +1 over adult when the ingredient has measurable absorption: adult e=1 → baby e=2. There is no direct evidence to increase hazard (h) or mechanism (m) for infants.
- Как VeriMom оценивает coptis japonica rhizome extract?
- VeriMom оценивает coptis japonica rhizome extract в 93/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы coptis japonica rhizome extract при беременности?
- См. наш список безопасных альтернатив coptis japonica rhizome extract с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.