Безопасен ли cocamidopropyl hydroxysultaine при беременности?
No harmonised reproductive classification or SCCS/CIR repro flag was identified. Repeated-dose/oral (OECD 422) studies reported a developmental/reproductive NOAEL around 300 mg/kg/day and agencies reviewing the data (registration dossiers / national assessments) concluded no developmental toxicity at doses ≤300 mg/kg/day, so there is no evidence of a reproductive hazard. For topical cosmetic use systemic absorption is expected to be low but measurable, so exposure is scored as low (e=1). Sources: ECHA registration dossier and national assessment. (ECHA OECD 422 dossier; Canada final assessment).
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Frequently asked questions
- Безопасен ли cocamidopropyl hydroxysultaine при беременности?
- No harmonised reproductive classification or SCCS/CIR repro flag was identified. Repeated-dose/oral (OECD 422) studies reported a developmental/reproductive NOAEL around 300 mg/kg/day and agencies reviewing the data (registration dossiers / national assessments) concluded no developmental toxicity at doses ≤300 mg/kg/day, so there is no evidence of a reproductive hazard. For topical cosmetic use systemic absorption is expected to be low but measurable, so exposure is scored as low (e=1). Sources: ECHA registration dossier and national assessment. (ECHA OECD 422 dossier; Canada final assessment).
- Безопасен ли cocamidopropyl hydroxysultaine при грудном вскармливании?
- No data indicating transfer to breastmilk or breastfeeding-specific adverse effects were found in authoritative dossiers or the published toxicology records. Animal studies show no reproductive/developmental hazard at relevant NOAELs; therefore hazard and mechanism scores are 0. Topical use implies low but measurable maternal systemic exposure, so breastfeeding exposure scored as low (e=1).
- Безопасен ли cocamidopropyl hydroxysultaine для кожи малыша?
- No infant-specific reproductive/toxic mechanism or developmental evidence was found. Because the ingredient has measurable absorption in systemic toxicity studies (oral) and topical cosmetics can be absorbed to a low extent in adults, infant skin (0–3 yr) — which has an immature barrier and higher surface-area-to-weight ratio — receives one point higher exposure (adult e=1 → baby e=2). No infant-specific hazards were identified in the searched sources.
- Как VeriMom оценивает cocamidopropyl hydroxysultaine?
- VeriMom оценивает cocamidopropyl hydroxysultaine в 93/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы cocamidopropyl hydroxysultaine при беременности?
- См. наш список безопасных альтернатив cocamidopropyl hydroxysultaine с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.