Безопасен ли cobamamide при беременности?

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Frequently asked questions

Безопасен ли cobamamide при беременности?

No harmonised CLP reproductive classification was identified for cobamamide and there are no credible data showing reproductive toxicity or teratogenicity for adenosylcobalamin; it is an active form of vitamin B12 which is considered required in pregnancy and routinely supplemented when deficient. Sources: vitamin B12 guidance and reviews, and database entries for adenosylcobalamin (see sources).

Безопасен ли cobamamide при грудном вскармливании?

Vitamin B12 compounds (including hydroxocobalamin/other B12 forms) are reported to be excreted into human milk but are not associated with reproductive or developmental toxicity; no evidence that cobamamide is harmful via maternal milk. No harmonised hazard classification found. Excretion into milk is established for some B12 forms, so systemic maternal dosing can lead to infant exposure, but this is nutritional rather than toxicological in nature.

Безопасен ли cobamamide для кожи малыша?

No evidence of reproductive or developmental hazard specifically in infants. Dermal exposure from cosmetics is expected to have negligible systemic hazard (h=0), but per guidance infant skin barrier immaturity increases potential exposure; adult topical absorption is expected to be negligible for this large, water-soluble B12 derivative, so baby exposure score is increased by +1 to e=1 to reflect higher surface-area-to-weight and immature barrier despite low adult absorption. No infant-specific dermal toxicity data were located.

Как VeriMom оценивает cobamamide?

VeriMom оценивает cobamamide в 100/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы cobamamide при беременности?

См. наш список безопасных альтернатив cobamamide с аналогичной функцией и классификацией без известных рисков.