Безопасен ли cimicifuga racemosa root extract при беременности?

Безопасные альтернативы cimicifuga racemosa root extract при беременности | VeriMom

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Безопасен ли cimicifuga racemosa root extract при беременности?

Black cohosh (Cimicifuga/Actaea racemosa) extracts have historical and reviewed evidence of uterotonic/hormonal activity and are cautioned against in pregnancy by EMA/HMPC and clinical reviews; no EU Annex II/III ban or harmonised H360/H361 classification was found. Evidence supports a mechanistic concern (triterpene glycosides with estrogenic/uterotonic activity) but not a harmonised reproductive hazard classification. (EMA HMPC; PubMed review; NTP report).

Безопасен ли cimicifuga racemosa root extract при грудном вскармливании?

HMPC/EMA and clinical reviews state safety in lactation is not established and note hormonal activity; theoretical/observational concerns exist but no harmonised CMR classification or definitive human teratogenic/lactation transfer data. Topical cosmetic exposure would likely give low systemic exposure. (EMA HMPC; PubMed review; NCCIH).

Безопасен ли cimicifuga racemosa root extract для кожи малыша?

No infant-specific absorption/toxicity data found. Given measurable systemic/hormonal activity reported for oral preparations, and immature infant skin barrier, exposure score increased by +1 for 0–3 y. No harmonised classification or EU ban; concerns remain theoretical/observational rather than confirmed. (EMA HMPC; NTP; clinical reviews).

Как VeriMom оценивает cimicifuga racemosa root extract?

VeriMom оценивает cimicifuga racemosa root extract в 60/100 (средний риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы cimicifuga racemosa root extract при беременности?

См. наш список безопасных альтернатив cimicifuga racemosa root extract с аналогичной функцией и классификацией без известных рисков.