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Безопасен ли chrysanthemum parthenium extract при беременности?

Feverfew (Chrysanthemum/Tanacetum parthenium) extracts contain the sesquiterpene lactone parthenolide, which has demonstrated biological activity (including uterine-stimulant/emmenagogue effects in traditional reports and embryo toxicity in an in vitro embryoculture screening) and is the basis for recommendations to avoid use in pregnancy; therefore reproductive hazard is scored as suspected (h=2). Evidence: a reproductive screening study and recent reviews note embryo toxicity signals and advise avoidance in pregnancy. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/16781113/?utm_source=openai))

Ингредиенты
chrysanthemum parthenium extract
СРЕДНИЙ РИСК
40
/100
0

Безопасные альтернативы chrysanthemum parthenium extract при беременности | VeriMom

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Frequently asked questions

Безопасен ли chrysanthemum parthenium extract при беременности?
Feverfew (Chrysanthemum/Tanacetum parthenium) extracts contain the sesquiterpene lactone parthenolide, which has demonstrated biological activity (including uterine-stimulant/emmenagogue effects in traditional reports and embryo toxicity in an in vitro embryoculture screening) and is the basis for recommendations to avoid use in pregnancy; therefore reproductive hazard is scored as suspected (h=2). Evidence: a reproductive screening study and recent reviews note embryo toxicity signals and advise avoidance in pregnancy. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/16781113/?utm_source=openai))
Безопасен ли chrysanthemum parthenium extract при грудном вскармливании?
There are no data on excretion of feverfew constituents into human milk; reviews and monographs state safety in lactation is unknown and recommend avoidance. Given the lack of direct data but the presence of active constituents (parthenolide) and traditional contraindication, this is scored as a low/suspected concern (h=1) with a theoretical mechanism (m=1). ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/30000921/?utm_source=openai))
Безопасен ли chrysanthemum parthenium extract для кожи малыша?
No infant-specific reproductive hazard data were identified; reproductive hazard scores are not increased for infants. Topical exposure absorption is measurable for botanical extracts and infants have higher skin absorption, so exposure is increased by +1 (adult e=1 → infant e=2). Note: feverfew/parthenolide is a known skin sensitizer in some people (contact dermatitis) which is a non‑reproductive safety concern for infants. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/19112586/?utm_source=openai))
Как VeriMom оценивает chrysanthemum parthenium extract?
VeriMom оценивает chrysanthemum parthenium extract в 40/100 (средний риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
Какие безопасные альтернативы chrysanthemum parthenium extract при беременности?
См. наш список безопасных альтернатив chrysanthemum parthenium extract с аналогичной функцией и классификацией без известных рисков.

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Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.

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