VeriMomБезопасен ли c26-28 alkyldimethylsilyl polypropylsilsesquioxane при беременности?
No harmonised CLP/Annex VI reproductive classification was found and the Cosmetic Ingredient Review (CIR) safety assessment for polysilsesquioxanes concludes these are large, insoluble polymeric silsesquioxanes used safely in cosmetics; no reproductive or developmental hazard data indicating risk in pregnancy were identified in the available literature (CIR). PubMed developmental work on a quaternary silsesquioxane showed no developmental toxicity in rats. ECHA does not list a harmonised repro classification for related silsesquioxanes. Sources: CIR polysilsesquioxanes safety assessment; PubMed developmental study; ECHA substance information.
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Frequently asked questions
- Безопасен ли c26-28 alkyldimethylsilyl polypropylsilsesquioxane при беременности?
- No harmonised CLP/Annex VI reproductive classification was found and the Cosmetic Ingredient Review (CIR) safety assessment for polysilsesquioxanes concludes these are large, insoluble polymeric silsesquioxanes used safely in cosmetics; no reproductive or developmental hazard data indicating risk in pregnancy were identified in the available literature (CIR). PubMed developmental work on a quaternary silsesquioxane showed no developmental toxicity in rats. ECHA does not list a harmonised repro classification for related silsesquioxanes. Sources: CIR polysilsesquioxanes safety assessment; PubMed developmental study; ECHA substance information.
- Безопасен ли c26-28 alkyldimethylsilyl polypropylsilsesquioxane при грудном вскармливании?
- No data showing systemic reproductive/toxic effects or demonstrated mammary/transfer to milk. CIR assessment finds these ingredients are large, insoluble polymers with low dermal absorption in typical cosmetic use, and no specific evidence of transfer into breast milk or lactation-specific harm was found.
- Безопасен ли c26-28 alkyldimethylsilyl polypropylsilsesquioxane для кожи малыша?
- CIR and product/INCI references describe these as large, polymeric, low-solubility silicones with low dermal absorption; therefore adult exposure is negligible (e=0). Because infant (0–3 yr) skin has a higher surface-area-to-weight ratio and an immature barrier, exposure score is increased by +1 per your scoring rules to e=1. No infant-specific toxicity or developmental evidence was identified.
- Как VeriMom оценивает c26-28 alkyldimethylsilyl polypropylsilsesquioxane?
- VeriMom оценивает c26-28 alkyldimethylsilyl polypropylsilsesquioxane в 100/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы c26-28 alkyldimethylsilyl polypropylsilsesquioxane при беременности?
- См. наш список безопасных альтернатив c26-28 alkyldimethylsilyl polypropylsilsesquioxane с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.