VeriMomБезопасен ли butyrolactone при беременности?
No harmonised reproductive classification (no H360/H361 on ECHA substance listing) and no CIR or SCCS reproductive safety opinion was found for butyrolactone/γ‑butyrolactone; available regulatory and safety documents describe acute toxicity and misuse risk on ingestion but do not identify reproductive teratogenicity from dermal/cosmetic use. Topical exposure could give low but measurable systemic exposure because GBL is a small, water‑miscible molecule that is absorbed and readily metabolised to GHB after systemic uptake, so exposure score is 1 for pregnancy (adult topical). Sources: ECHA substance page; SDSs/regulatory summaries; CDC/FDA reviews of ingestion risks.
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Frequently asked questions
- Безопасен ли butyrolactone при беременности?
- No harmonised reproductive classification (no H360/H361 on ECHA substance listing) and no CIR or SCCS reproductive safety opinion was found for butyrolactone/γ‑butyrolactone; available regulatory and safety documents describe acute toxicity and misuse risk on ingestion but do not identify reproductive teratogenicity from dermal/cosmetic use. Topical exposure could give low but measurable systemic exposure because GBL is a small, water‑miscible molecule that is absorbed and readily metabolised to GHB after systemic uptake, so exposure score is 1 for pregnancy (adult topical). Sources: ECHA substance page; SDSs/regulatory summaries; CDC/FDA reviews of ingestion risks.
- Безопасен ли butyrolactone при грудном вскармливании?
- No authoritative reproductive/breastfeeding safety assessment (CIR/SCCS/harmonised CLP) flagging developmental or lactation hazards. Systemic exposure from topical use is expected to be low but measurable in adults; because GBL converts to GHB systemically, breastmilk transfer would only be a concern if significant maternal systemic levels occur (not typical from normal cosmetic topical use). Thus hazard/mechanism remain 0; exposure scored 1 (low but measurable). Sources: ECHA substance information; LactMed/GHB references and FDA/CDC warnings about systemic effects from ingestion rather than topical use.
- Безопасен ли butyrolactone для кожи малыша?
- No infant‑specific reproductive/developmental toxicity evidence from authoritative cosmetic safety bodies. Per scoring rules, because adult topical exposure is scored as 1 (measurable), infant skin exposure is increased by +1 (immature barrier and higher SA:BW) to give e=2 (moderate). There is no infant‑specific data showing placental or dermal developmental hazards; the main concern in literature is systemic GHB effects after ingestion/large exposures, not routine topical cosmetic use. Sources: ECHA substance page; EPA/EPA inert reassessment and SDSs describing routes of concern (ingestion/systemic), and EWG ingredient entry.
- Как VeriMom оценивает butyrolactone?
- VeriMom оценивает butyrolactone в 93/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы butyrolactone при беременности?
- См. наш список безопасных альтернатив butyrolactone с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.