VeriMomБезопасен ли borago officinalis leaf extract при беременности?
No EU Cosmetic Regulation ban (Annex II) or Annex III restriction or harmonised CLP H360/H361 was identified for Borago officinalis leaf extract. However, the plant family (Boraginaceae) is known to produce pyrrolizidine alkaloids (PAs) which have demonstrated toxic and genotoxic mechanisms in animals and humans; this represents a class-based concern (h=1) with a demonstrated mechanism (m=2). Topical cosmetic use of a leaf extract is likely low but measurable exposure (e=1). Sources: EU INCI listing for Borago Officinalis Extract, PubMed reviews on borage/PAs, and EWG ingredient summary.
Безопасные альтернативы borago officinalis leaf extract при беременности | VeriMom
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- Безопасен ли borago officinalis leaf extract при беременности?
- No EU Cosmetic Regulation ban (Annex II) or Annex III restriction or harmonised CLP H360/H361 was identified for Borago officinalis leaf extract. However, the plant family (Boraginaceae) is known to produce pyrrolizidine alkaloids (PAs) which have demonstrated toxic and genotoxic mechanisms in animals and humans; this represents a class-based concern (h=1) with a demonstrated mechanism (m=2). Topical cosmetic use of a leaf extract is likely low but measurable exposure (e=1). Sources: EU INCI listing for Borago Officinalis Extract, PubMed reviews on borage/PAs, and EWG ingredient summary.
- Безопасен ли borago officinalis leaf extract при грудном вскармливании?
- Same rationale as pregnancy: no regulatory ban or harmonised reproductive classification found, but PA-related hepatotoxic/genotoxic concerns for Borago officinalis warrant a class-level caution (h=1). Mechanistic evidence for PA toxicity exists (m=2). Topical use implies low but measurable exposure (e=1); systemic transfer into breastmilk after dermal cosmetic use has not been demonstrated.
- Безопасен ли borago officinalis leaf extract для кожи малыша?
- Hazard (h=1) remains driven by the plant’s PA class concern rather than any infant-specific reproductive data. Mechanistic concern from PAs (m=2) remains. Exposure is increased for babies (elevated by +1 to e=2) because infant skin has higher surface-area-to-weight and an immature barrier, so topical absorption (if any) is proportionally higher even though absolute systemic exposure from a cosmetic extract is expected to be low.
- Как VeriMom оценивает borago officinalis leaf extract?
- VeriMom оценивает borago officinalis leaf extract в 60/100 (средний риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы borago officinalis leaf extract при беременности?
- См. наш список безопасных альтернатив borago officinalis leaf extract с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.