Безопасен ли bis-hea polycaprolactone diol/hdi copolymer при беременности?

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Безопасен ли bis-hea polycaprolactone diol/hdi copolymer при беременности?

No harmonised CLP reproductive classifications (ECHA Annex VI) or SCCS/CIR safety assessments were identified for this CAS. The substance is a high‑molecular‑weight urethane/ polycaprolactone copolymer (polymeric), for which there is no reproductive/teratogenic evidence in regulatory databases or peer‑reviewed literature. Polymers of this type have low systemic bioavailability when used topically, supporting low exposure to the fetus.

Безопасен ли bis-hea polycaprolactone diol/hdi copolymer при грудном вскармливании?

No data indicate reproductive or lactation toxicity, and no harmonised classifications. High molecular weight polymeric ingredients are generally poorly absorbed and unlikely to reach breast milk. No SCCS/CIR opinion or peer‑reviewed studies showing transfer into milk were found.

Безопасен ли bis-hea polycaprolactone diol/hdi copolymer для кожи малыша?

Hazard and mechanism: no specific pediatric reproductive or developmental toxicity data were identified for this ingredient. Exposure: although adult topical absorption is expected to be negligible for a high‑MW polymer, infant skin has higher permeability and surface‑area‑to‑weight ratio; therefore exposure score increased by +1 (adult e=0 → infant e=1). This assumes no evidence of significant dermal absorption of the polymer itself.

Как VeriMom оценивает bis-hea polycaprolactone diol/hdi copolymer?

VeriMom оценивает bis-hea polycaprolactone diol/hdi copolymer в 100/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы bis-hea polycaprolactone diol/hdi copolymer при беременности?

См. наш список безопасных альтернатив bis-hea polycaprolactone diol/hdi copolymer с аналогичной функцией и классификацией без известных рисков.