Безопасен ли artemisia annua extract при беременности?

Безопасные альтернативы artemisia annua extract при беременности | VeriMom

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Безопасен ли artemisia annua extract при беременности?

Artemisia annua extracts can contain artemisinin-class compounds, which produce severe embryotoxicity and developmental effects in multiple animal species; WHO and systematic reviews cite animal embryotoxicity/teratogenicity for artemisinin derivatives and advise caution in early pregnancy. There is no EU Annex II/III ban or harmonised CLP for the botanical extract itself, but the demonstrated animal reproductive toxicity of artemisinin (a likely component) justifies a 'suspected' reproductive hazard. (Sources: WHO nonclinical overview; systematic reviews and PubMed reviews).

Безопасен ли artemisia annua extract при грудном вскармливании?

Direct data on transfer of Artemisia annua extract or artemisinin into human milk are limited. Given the known animal embryo/foetal effects for artemisinin derivatives, a theoretical/class-based concern exists for breastfeeding exposure (precautionary), but there is insufficient direct evidence of harm via breastmilk in humans. Exposure from topical cosmetic use is expected to be low but measurable. (Sources: WHO review; clinical reviews summarising limited human/breastfeeding data).

Безопасен ли artemisia annua extract для кожи малыша?

No infant-specific safety studies for topical Artemisia annua extract were found. Because the extract may contain artemisinin-class molecules that have demonstrated systemic embryotoxic mechanisms (affecting primitive erythroblasts and angiogenesis) and because infant skin has higher absorption per kg, the hazard and mechanistic concern are carried over from adult data (h=2, m=2) while exposure is increased by one category for infants (e increased). There is no evidence (e.g., harmonised CLP or EU ban) specific to cosmetic topical use to lower this concern. (Sources: WHO, systematic reviews, CosIng/EU listings, EWG).

Как VeriMom оценивает artemisia annua extract?

VeriMom оценивает artemisia annua extract в 40/100 (средний риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы artemisia annua extract при беременности?

См. наш список безопасных альтернатив artemisia annua extract с аналогичной функцией и классификацией без известных рисков.