Безопасен ли apium graveolens seed extract при беременности?
No evidence found of EU cosmetic bans/restrictions (Annex II/III) or harmonised reproductive hazard classification for Apium graveolens seed extract (CAS 89997-35-3). Cosmetic databases list the INCI (CosIng) and EWG lists the ingredient but do not flag reproductive toxicity. Peer-reviewed studies on major celery seed constituents (e.g., 3‑n‑butylphthalide) report pharmacology/toxicity data after oral dosing but do not support a confirmed reproductive teratogen classification; therefore hazard (h)=0 and mechanism (m)=0. Topical exposure has low but measurable absorption potential (botanical volatiles/constituents), so exposure (e)=1 for pregnancy (adult topical use). Sources: CosIng entry, EWG entry, PubMed pharmacology/toxicity studies, supplier/CAS listings.
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Frequently asked questions
- Безопасен ли apium graveolens seed extract при беременности?
- No evidence found of EU cosmetic bans/restrictions (Annex II/III) or harmonised reproductive hazard classification for Apium graveolens seed extract (CAS 89997-35-3). Cosmetic databases list the INCI (CosIng) and EWG lists the ingredient but do not flag reproductive toxicity. Peer-reviewed studies on major celery seed constituents (e.g., 3‑n‑butylphthalide) report pharmacology/toxicity data after oral dosing but do not support a confirmed reproductive teratogen classification; therefore hazard (h)=0 and mechanism (m)=0. Topical exposure has low but measurable absorption potential (botanical volatiles/constituents), so exposure (e)=1 for pregnancy (adult topical use). Sources: CosIng entry, EWG entry, PubMed pharmacology/toxicity studies, supplier/CAS listings.
- Безопасен ли apium graveolens seed extract при грудном вскармливании?
- No specific data indicating reproductive or lactation/transfer hazards; no harmonised H361/H360 or EU Annex II/III listing. Mechanistic data for placental/milk transfer are lacking; topical exposure to breastfeeding parent is therefore low but measurable (e=1). Same rationale as pregnancy.
- Безопасен ли apium graveolens seed extract для кожи малыша?
- No infant-specific reproductive or developmental toxicity data found for topical Apium graveolens seed extract. Because infant skin (0–3 yr) has higher absorption/surface‑area‑to‑weight and the ingredient can contain lipophilic/volatile constituents, I increase exposure score by +1 relative to adults (adult e=1 → infant e=2). No evidence found that justifies increasing hazard (h) or mechanism (m) for infants.
- Как VeriMom оценивает apium graveolens seed extract?
- VeriMom оценивает apium graveolens seed extract в 93/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы apium graveolens seed extract при беременности?
- См. наш список безопасных альтернатив apium graveolens seed extract с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.