VeriMomБезопасен ли acorus calamus root extract при беременности?
Acorus calamus extracts contain phenylpropanoids (notably β‑asarone) that have been demonstrated carcinogenic/genotoxic and developmental effects in animal models and in vitro (see review and primary studies). There is no EU Annex II ban or harmonised CLP CMR classification found, but animal carcinogenicity/genotoxicity and some developmental signals justify a suspected reproductive/teratogenic hazard (h=2) and a demonstrated mechanism (m=2). Topical cosmetic use gives low but measurable systemic exposure in adults (e=1). Sources: peer‑reviewed toxicology review (PMC9761896), animal studies and genotoxicity reports, and Council of Europe / flavoring safety discussions (see sources).
Безопасные альтернативы acorus calamus root extract при беременности | VeriMom
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Frequently asked questions
- Безопасен ли acorus calamus root extract при беременности?
- Acorus calamus extracts contain phenylpropanoids (notably β‑asarone) that have been demonstrated carcinogenic/genotoxic and developmental effects in animal models and in vitro (see review and primary studies). There is no EU Annex II ban or harmonised CLP CMR classification found, but animal carcinogenicity/genotoxicity and some developmental signals justify a suspected reproductive/teratogenic hazard (h=2) and a demonstrated mechanism (m=2). Topical cosmetic use gives low but measurable systemic exposure in adults (e=1). Sources: peer‑reviewed toxicology review (PMC9761896), animal studies and genotoxicity reports, and Council of Europe / flavoring safety discussions (see sources).
- Безопасен ли acorus calamus root extract при грудном вскармливании?
- Same basis as pregnancy: systemic uptake of toxic constituents (β‑asarone) in people exposed systemically could pose risk to nursing infants via transfer in milk; mechanism (genotoxic/metabolic activation) is demonstrated in animal/in vitro studies, and exposure from topical use is expected low but measurable (e=1). No specific human lactation studies were identified.
- Безопасен ли acorus calamus root extract для кожи малыша?
- Hazard and mechanistic evidence are the same (β‑asarone genotoxic/carcinogenic and some developmental effects), so h and m remain suspected/demonstrated. Exposure score is increased by +1 for infants (immature barrier and higher surface‑area‑to‑weight): adult topical e=1 → infant e=2. There are no infant‑specific safety studies showing safe topical use.
- Как VeriMom оценивает acorus calamus root extract?
- VeriMom оценивает acorus calamus root extract в 40/100 (средний риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы acorus calamus root extract при беременности?
- См. наш список безопасных альтернатив acorus calamus root extract с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.