VeriMomБезопасен ли 7-dehydrocholesterol при беременности?
No harmonised CLP reproductive classification (ECHA brief profile shows registrations/self‑notifications but no Annex VI harmonised classification) and no SCCS/CIR reproductive safety restriction found. 7‑DHC is an endogenous cholesterol/vitamin D3 precursor; peer‑reviewed studies describe its role and that elevated systemic 7‑DHC is associated with genetic DHCR7 defects (Smith‑Lemli‑Opitz syndrome) or drug inhibition of DHCR7, but there is no evidence that topical cosmetic use of 7‑DHC causes reproductive toxicity in pregnant humans or animals. Topical absorption is possible for a lipophilic sterol but expected to be low, so exposure score = 1. (Sources: ECHA brief profile; PubMed sterol/7‑DHC studies; EWG ingredient page).
Pregnancy-safe products containing 7-dehydrocholesterol
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Frequently asked questions
- Безопасен ли 7-dehydrocholesterol при беременности?
- No harmonised CLP reproductive classification (ECHA brief profile shows registrations/self‑notifications but no Annex VI harmonised classification) and no SCCS/CIR reproductive safety restriction found. 7‑DHC is an endogenous cholesterol/vitamin D3 precursor; peer‑reviewed studies describe its role and that elevated systemic 7‑DHC is associated with genetic DHCR7 defects (Smith‑Lemli‑Opitz syndrome) or drug inhibition of DHCR7, but there is no evidence that topical cosmetic use of 7‑DHC causes reproductive toxicity in pregnant humans or animals. Topical absorption is possible for a lipophilic sterol but expected to be low, so exposure score = 1. (Sources: ECHA brief profile; PubMed sterol/7‑DHC studies; EWG ingredient page).
- Безопасен ли 7-dehydrocholesterol при грудном вскармливании?
- No evidence that topical 7‑DHC is a reproductive toxicant or that it produces adverse effects via breastmilk. Mechanistic/reproductive hazards are associated with systemic elevation of 7‑DHC caused by genetic DHCR7 deficiency or certain drugs that inhibit DHCR7, not by topical application. Systemic absorption from typical topical cosmetic use is expected to be low but measurable (e=1).
- Безопасен ли 7-dehydrocholesterol для кожи малыша?
- No infant‑specific studies showing reproductive or developmental toxicity from topical 7‑DHC. Because 7‑DHC is a skin sterol/provitamin D3 present endogenously and topical absorption of lipophilic sterols is measurable, infant exposure via skin is higher than adults (immature barrier and higher surface‑area:weight), so exposure score is increased by +1 (adult e=1 → baby e=2). No evidence found that baby skin exposure causes harm at cosmetic use levels; however systemic elevation of 7‑DHC from DHCR7 disruption is a known hazard in genetic disease and medication interactions (not a topical‑cosmetic finding).
- Как VeriMom оценивает 7-dehydrocholesterol?
- VeriMom оценивает 7-dehydrocholesterol в 93/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы 7-dehydrocholesterol при беременности?
- См. наш список безопасных альтернатив 7-dehydrocholesterol с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.