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Безопасен ли 2-bromo-2-nitropropane-1,3-diol (formaldehyde releaser) при беременности?

CIR amended safety assessment concluded bronopol (2‑bromo‑2‑nitropropane‑1,3‑diol) is safe in cosmetics at reported use concentrations (≤0.1%) and reported animal reproductive studies showed no consistent teratogenicity or impaired fertility at relevant doses; no harmonised reproductive classification (H360/H361 harmonised) was identified in Annex VI for reproductive effects. Dermal exposure from cosmetic use is low but measurable, so exposure score=1. (CIR; ECHA; animal studies summarized in CIR).

Ингредиенты
2-bromo-2-nitropropane-1,3-diol (formaldehyde releaser)
БЕЗ ИЗВЕСТНЫХ РИСКОВ
93
/100
0

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Frequently asked questions

Безопасен ли 2-bromo-2-nitropropane-1,3-diol (formaldehyde releaser) при беременности?
CIR amended safety assessment concluded bronopol (2‑bromo‑2‑nitropropane‑1,3‑diol) is safe in cosmetics at reported use concentrations (≤0.1%) and reported animal reproductive studies showed no consistent teratogenicity or impaired fertility at relevant doses; no harmonised reproductive classification (H360/H361 harmonised) was identified in Annex VI for reproductive effects. Dermal exposure from cosmetic use is low but measurable, so exposure score=1. (CIR; ECHA; animal studies summarized in CIR).
Безопасен ли 2-bromo-2-nitropropane-1,3-diol (formaldehyde releaser) при грудном вскармливании?
No clinical or animal evidence indicating specific lactation/transfer risks or human developmental toxicity at cosmetic use levels in the cited assessments; CIR found no reproductive/teratogenic concern at normal cosmetic concentrations. Dermal absorption from cosmetics is low but measurable, so exposure score=1. (CIR; animal studies summarized in CIR).
Безопасен ли 2-bromo-2-nitropropane-1,3-diol (formaldehyde releaser) для кожи малыша?
No infant‑specific reproductive or developmental hazard data were found; CIR safety assessment and animal studies do not indicate developmental/teratogenic hazard at cosmetic use levels. Because infant skin has higher surface‑area‑to‑weight and an immature barrier and bronopol has measurable dermal activity in irritation/sensitization tests, exposure score is increased by +1 for ages 0–3 (adult e=1 → baby e=2). Note also documented risks for contact allergy and potential formation of small amounts of formaldehyde/nitrite under certain conditions (relevant for skin sensitivity). (CIR; PubMed patch‑test studies; EWG).
Как VeriMom оценивает 2-bromo-2-nitropropane-1,3-diol (formaldehyde releaser)?
VeriMom оценивает 2-bromo-2-nitropropane-1,3-diol (formaldehyde releaser) в 93/100 (без известных рисков) на основе EU CosIng, классификаций ECHA и исследований PubMed.
Какие безопасные альтернативы 2-bromo-2-nitropropane-1,3-diol (formaldehyde releaser) при беременности?
См. наш список безопасных альтернатив 2-bromo-2-nitropropane-1,3-diol (formaldehyde releaser) с аналогичной функцией и классификацией без известных рисков.

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Медицинская оговорка

Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.

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