Стоит ли избегать silybum marianum extract при беременности? | VeriMom

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FAQ

Безопасен ли silybum marianum extract при беременности?

No harmonised CLP classification (no H360/H361 harmonised entry found), no EU Annex II/III restriction for Silybum marianum extract. Recent reviews and animal studies show either absence of reproductive/developmental toxicity or protective effects from silymarin; human data in pregnancy are scarce so regulators (NCCIH/EMA summaries) caution use but do not list a reproductive hazard. Topical cosmetic use would give low but measurable exposure. Sources: PubMed reviews and animal studies, NCCIH, ECHA registration summary. (PubMed review: Protective effects of silymarin on reproductive toxicity; animal developmental study: silymarin during pregnancy/lactation; NCCIH: limited data on pregnancy/breastfeeding; ECHA registration/listing shows registration dossier but no harmonised H361 classification).

Безопасен ли silybum marianum extract при грудном вскармливании?

Human data are limited. Some small/unpublished reports suggest low or non‑measurable excretion of silymarin into breastmilk, but evidence is insufficient and agencies advise caution. Topical cosmetic exposure would result in low systemic levels for the lactating parent, so infant exposure via milk from topical use is expected to be low but not zero. (Sources: NCCIH, EFSA/EFSA‑referenced report, PubMed studies).

Безопасен ли silybum marianum extract для кожи малыша?

No direct evidence of developmental or infant dermal toxicity. Because infants 0–3 years have a thinner/immature skin barrier and higher surface‑area‑to‑body‑weight, exposure score is increased by +1 compared with adults if the ingredient has measurable absorption. Silymarin components are moderately lipophilic and can be absorbed to a small degree; therefore infant dermal exposure is assessed as moderate. No infant‑specific hazards or CMR classifications were identified. (Sources: PubMed reviews, ECHA registration dossier, EWG ingredient page).

Как VeriMom оценивает silybum marianum extract?

VeriMom оценивает silybum marianum extract в 33/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы silybum marianum extract при беременности?

См. наш список безопасных альтернатив silybum marianum extract с аналогичной функцией и классификацией без известных рисков.