Стоит ли избегать propylene glycol dicaprate при беременности? | VeriMom

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли propylene glycol dicaprate при беременности?

Authoritative CIR safety assessment of propylene glycol esters (which includes propylene glycol dicaprate/dicaprylate) reports no reproductive or developmental effects in a rat prenatal study (gavage to 1000 mg/kg/day) and concludes acceptable safety in cosmetics; no harmonised ECHA Annex VI classification (H360/H361) for this substance was found. Dermal/systemic exposure from cosmetic use is low but measurable (used in leave‑on products, and some PG diesters can enhance dermal penetration in vitro, though dicaprylate did not increase penetration of water‑soluble drugs in the CIR review). ([cir-safety.org](https://www.cir-safety.org/sites/default/files/PGEste_122014_FR.pdf))

Безопасен ли propylene glycol dicaprate при грудном вскармливании?

No data indicating reproductive toxicity, lactation-specific toxicity, or mechanisms for transfer to breast milk were identified in authoritative reviews. Given low systemic absorption from topical use reported in the CIR review, maternal systemic exposure (and therefore milk transfer) is expected to be low but measurable. ([cir-safety.org](https://www.cir-safety.org/sites/default/files/PGEste_122014_FR.pdf))

Безопасен ли propylene glycol dicaprate для кожи малыша?

CIR documents reported uses of propylene glycol dicaprylate/dicaprate in baby lotions (reported use concentrations historically ~2.5%) and includes dermal data; no infant-specific reproductive or developmental harms were found. Because infant skin has higher surface‑area‑to‑weight and an immature barrier, exposure rating is increased by +1 versus adults (from low/measurable to moderate). No infant‑specific adverse data or mechanistic evidence were found. ([cir-safety.org](https://www.cir-safety.org/sites/default/files/PGEste_122014_FR.pdf))

Как VeriMom оценивает propylene glycol dicaprate?

VeriMom оценивает propylene glycol dicaprate в 33/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы propylene glycol dicaprate при беременности?

См. наш список безопасных альтернатив propylene glycol dicaprate с аналогичной функцией и классификацией без известных рисков.