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Стоит ли избегать pentasodium pentetate при беременности? | VeriMom

EU harmonised CLP classification lists pentasodium pentetate (CAS 140-01-2) as Reproductive toxicant Category 1B (H360D) (Commission Delegated Regulation / Annex VI update). The CIR safety assessment (2008) concluded low likelihood of dermal penetration and reported animal reproductive NOAELs, but harmonised EU classification (based on later assessment) indicates a H360-level evidence of reproductive toxicity, so hazard is scored 3. Dermal exposure from cosmetics is considered negligible based on CIR (low dermal penetration).

ECHA regulatory hazard statements

  • H360D

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли pentasodium pentetate при беременности?
EU harmonised CLP classification lists pentasodium pentetate (CAS 140-01-2) as Reproductive toxicant Category 1B (H360D) (Commission Delegated Regulation / Annex VI update). The CIR safety assessment (2008) concluded low likelihood of dermal penetration and reported animal reproductive NOAELs, but harmonised EU classification (based on later assessment) indicates a H360-level evidence of reproductive toxicity, so hazard is scored 3. Dermal exposure from cosmetics is considered negligible based on CIR (low dermal penetration).
Безопасен ли pentasodium pentetate при грудном вскармливании?
Because pentasodium pentetate has a harmonised H360 classification (Repr. 1B), reproductive hazard is scored 3 for lactation context as well. There is no mechanistic or human lactation-specific data showing transfer into human milk, and CIR concluded likely low dermal penetration for cosmetic use, so exposure from topical cosmetics is scored 0.
Безопасен ли pentasodium pentetate для кожи малыша?
Hazard remains 3 because of harmonised H360 classification. Mechanistic evidence for reproductive action is not reported. CIR concluded dermal penetration is likely low but not strictly zero; per scoring rules infant exposure is increased by +1 relative to adults when measurable absorption cannot be excluded, so exposure for baby skin is scored 1.
Как VeriMom оценивает pentasodium pentetate?
VeriMom оценивает pentasodium pentetate в 39/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
Какие безопасные альтернативы pentasodium pentetate при беременности?
См. наш список безопасных альтернатив pentasodium pentetate с аналогичной функцией и классификацией без известных рисков.

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Медицинская оговорка

Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.

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