VeriMomСтоит ли избегать laevo-rose oxide при беременности? | VeriMom
ECHA/industry sources and multiple product SDS list H361 (‘Suspected of damaging fertility or the unborn child’) for laevo‑(cis) rose oxide (CAS 3033‑23‑6), and ECHA registration dossiers report repeat‑dose studies noting testicular effects in rats (NOAELs cited in registrant summaries). This supports a suspected reproductive hazard (H361 → h=2). Systemic mechanism is supported by animal reproductive/toxicology findings (demonstrated effects in rodents), so m=2; dermal/topical cosmetic exposure is likely low but measurable, so e=1. Sources: ECHA registration/dossier summaries and product SDS (BASF/Axxence) and a recent review/biomonitoring summary noting animal testis effects.
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли laevo-rose oxide при беременности?
- ECHA/industry sources and multiple product SDS list H361 (‘Suspected of damaging fertility or the unborn child’) for laevo‑(cis) rose oxide (CAS 3033‑23‑6), and ECHA registration dossiers report repeat‑dose studies noting testicular effects in rats (NOAELs cited in registrant summaries). This supports a suspected reproductive hazard (H361 → h=2). Systemic mechanism is supported by animal reproductive/toxicology findings (demonstrated effects in rodents), so m=2; dermal/topical cosmetic exposure is likely low but measurable, so e=1. Sources: ECHA registration/dossier summaries and product SDS (BASF/Axxence) and a recent review/biomonitoring summary noting animal testis effects.
- Безопасен ли laevo-rose oxide при грудном вскармливании?
- Same hazard basis as for pregnancy (H361 reported by ECHA/SDS and animal data). Because route is systemic (possible placental/testicular effects in animals) there is potential for maternal systemic exposure after dermal absorption; however topical cosmetic use gives low but measurable systemic exposure so e=1. There are no human breastfeeding transfer data identified.
- Безопасен ли laevo-rose oxide для кожи малыша?
- Hazard and mechanism retain the same weight (H361 / animal reproductive effects). Exposure (e) is increased for infants: where adult dermal e=1, immature infant skin and higher surface‑area‑to‑weight justify +1 → e=2. No infant‑specific safety data were found; caution advised for leave‑on products applied to infants.
- Как VeriMom оценивает laevo-rose oxide?
- VeriMom оценивает laevo-rose oxide в 20/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы laevo-rose oxide при беременности?
- См. наш список безопасных альтернатив laevo-rose oxide с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.