Стоит ли избегать acetyl benzoyloxy prasterone при беременности? | VeriMom

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Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли acetyl benzoyloxy prasterone при беременности?

No EU Annex II/III ban or harmonised CLP classification was found for this CAS; however the compound is a prasterone (DHEA) ester and prasterone has androgen/estrogen activity in humans (medicinal use). Steroidal hormonal activity implies suspected reproductive/developmental hazard for pregnancy (calibration: demonstrated endocrine activity → h=2). There are clinical/peer-reviewed sources describing prasterone as an active steroid. No harmonised H360/H361 or Annex II listing was found for this specific derivative. (Sources: PubMed prasterone review; INCI/Gazzetta INCI listing.)

Безопасен ли acetyl benzoyloxy prasterone при грудном вскармливании?

Same rationale as pregnancy: the derivative can be expected to act (or be metabolised to) a steroid hormone (prasterone) with potential to reach systemic circulation; steroids may be transferred into breastmilk and affect nursing infants—this produces a suspected hazard in breastfeeding (h=2). No direct breastfeeding-specific studies on this derivative were located. (Sources: prasterone clinical literature; INCI lists.)

Безопасен ли acetyl benzoyloxy prasterone для кожи малыша?

Hazard and mechanism scores reflect the steroidal parent (prasterone) activity (suspected endocrine/reproductive hazard). Exposure score is increased for infant skin: topical steroidal molecules or esters that are measurably absorbable in adults are likely to have higher per-bodyweight exposure in infants with immature barrier function—so adult e=2 (moderate absorption expected for a lipophilic steroid-ester), infant e elevated to 3 per instructions. No infant-specific dermal studies for this compound were found. (Sources: INCI / cosmetic ingredient databases; prasterone clinical literature.)

Как VeriMom оценивает acetyl benzoyloxy prasterone?

VeriMom оценивает acetyl benzoyloxy prasterone в 33/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы acetyl benzoyloxy prasterone при беременности?

См. наш список безопасных альтернатив acetyl benzoyloxy prasterone с аналогичной функцией и классификацией без известных рисков.