VeriMomspironolactone est-il sûr pendant la grossesse ?
Spironolactone has a harmonised CLP reproductive toxicity classification (H360 — 'May damage fertility or the unborn child') on ECHA records/annex listings, and animal and case-report data support anti‑androgenic effects on fetal sexual development; mechanism is well characterised (anti‑androgenic activity demonstrated in vivo). Topical cosmetic use would usually give low systemic exposure compared with oral therapeutic dosing, so exposure from typical topical cosmetic use is judged low but measurable. Sources: ECHA CLP/harmonised listing, FDA product label, animal/human reports (PubMed/PMC).
Alternatives sûres à spironolactone pendant la grossesse | VeriMom
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Frequently asked questions
- spironolactone est-il sûr pendant la grossesse ?
- Spironolactone has a harmonised CLP reproductive toxicity classification (H360 — 'May damage fertility or the unborn child') on ECHA records/annex listings, and animal and case-report data support anti‑androgenic effects on fetal sexual development; mechanism is well characterised (anti‑androgenic activity demonstrated in vivo). Topical cosmetic use would usually give low systemic exposure compared with oral therapeutic dosing, so exposure from typical topical cosmetic use is judged low but measurable. Sources: ECHA CLP/harmonised listing, FDA product label, animal/human reports (PubMed/PMC).
- spironolactone est-il sûr pendant l'allaitement ?
- Intrinsic hazard remains at H360 level (may damage the unborn child/fertility). Mechanism (anti‑androgenic activity / endocrine effects) is well characterised. Clinical/lactation databases (LactMed, NHS) report low transfer of spironolactone into breast milk and no consistent adverse effects in reported infants at therapeutic maternal doses, so exposure to a breastfed infant from maternal systemic dosing is generally low; for cosmetic topical use systemic levels would be expected to be lower still (low but potentially measurable).
- spironolactone est-il sûr pour la peau de bébé ?
- The substance carries harmonised H360 (intrinsic reproductive hazard) so hazard score is 3. Mechanistic anti‑androgenic activity is well characterised. Exposure for infants (0–3 yr) is higher than adults for a given topical exposure because of immature barrier and higher surface‑area‑to‑weight; therefore exposure score is increased by one compared with adult topical use (adult topical e=1 → infant e=2). There is no infant‑specific evidence to change hazard or mechanism scores.
- Comment VeriMom évalue-t-il spironolactone ?
- VeriMom évalue spironolactone à 13/100 (risque élevé) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à spironolactone pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à spironolactone basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.