pueraria lobata root extract est-il sûr pendant la grossesse ?
Pueraria lobata root extract contains isoflavones (notably puerarin, daidzein, genistein) that show estrogenic activity in vitro and have produced reproductive/anti‑implantation effects in animal studies (rats). These animal reproductive findings justify a 'suspected' reproductive hazard (h=2) and indicate a demonstrated endocrine mechanism (m=2). Dermal exposure from cosmetics is expected to be low but measurable (e=1). Sources: Reproduction (puerarin disrupts pregnancy in rats) and in vitro estrogenic studies. (see sources).
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- pueraria lobata root extract est-il sûr pendant la grossesse ?
- Pueraria lobata root extract contains isoflavones (notably puerarin, daidzein, genistein) that show estrogenic activity in vitro and have produced reproductive/anti‑implantation effects in animal studies (rats). These animal reproductive findings justify a 'suspected' reproductive hazard (h=2) and indicate a demonstrated endocrine mechanism (m=2). Dermal exposure from cosmetics is expected to be low but measurable (e=1). Sources: Reproduction (puerarin disrupts pregnancy in rats) and in vitro estrogenic studies. (see sources).
- pueraria lobata root extract est-il sûr pendant l'allaitement ?
- Same hazard and mechanism apply for lactating people because the active constituents are phytoestrogens with demonstrated endocrine activity in animals/in vitro. Topical application to the breast would give low but measurable exposure to the parent; systemic transfer into milk is plausible for small lipophilic isoflavones but direct human lactation data are lacking, so exposure is rated low (e=1). Animal reproductive/lactation-specific data are limited. See cited animal and in vitro studies.
- pueraria lobata root extract est-il sûr pour la peau de bébé ?
- Hazard and mechanism remain 'suspected' (h=2/m=2) because the extract contains phytoestrogens shown to have reproductive effects in animals and estrogenic activity in vitro. Absorption concern is increased for infants (immature skin barrier and higher surface‑area‑to‑weight); therefore exposure is increased by +1 to e=2 even though absolute dermal absorption data for the extract are limited. No infant‑specific toxicity studies were identified.
- Comment VeriMom évalue-t-il pueraria lobata root extract ?
- VeriMom évalue pueraria lobata root extract à 40/100 (risque moyen) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à pueraria lobata root extract pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à pueraria lobata root extract basée sur une fonction similaire et une classification sans risques connus.
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Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.