VeriMomn,n'-dimethyl-n-hydroxyethyl-3-nitro-p-phenylenediamine est-il sûr pendant la grossesse ?
No harmonised CLP reproductive classifications (H360/H361) or SCCS/CIR safety assessment specific to CAS 10228-03-2 were identified. Regulatory sources show this specific compound (N,N'-dimethyl-N-hydroxyethyl-3‑nitro-p‑phenylenediamine; CAS 10228-03-2) is listed in EU/Member‑state cosmetic prohibitions for use in hair‑dye products, but that listing does not equal a harmonised reproductive hazard classification; peer‑reviewed reproductive or developmental studies on this exact substance were not found. Dermal absorption data are available for the p‑phenylenediamine class (measurable but low percent systemic absorption in human/in vitro studies), so for topical use a low but measurable exposure is assigned. Sources: EU cosmetics annex/regulatory listings and dermal absorption studies of p‑phenylenediamine. (See sources.)
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Frequently asked questions
- n,n'-dimethyl-n-hydroxyethyl-3-nitro-p-phenylenediamine est-il sûr pendant la grossesse ?
- No harmonised CLP reproductive classifications (H360/H361) or SCCS/CIR safety assessment specific to CAS 10228-03-2 were identified. Regulatory sources show this specific compound (N,N'-dimethyl-N-hydroxyethyl-3‑nitro-p‑phenylenediamine; CAS 10228-03-2) is listed in EU/Member‑state cosmetic prohibitions for use in hair‑dye products, but that listing does not equal a harmonised reproductive hazard classification; peer‑reviewed reproductive or developmental studies on this exact substance were not found. Dermal absorption data are available for the p‑phenylenediamine class (measurable but low percent systemic absorption in human/in vitro studies), so for topical use a low but measurable exposure is assigned. Sources: EU cosmetics annex/regulatory listings and dermal absorption studies of p‑phenylenediamine. (See sources.)
- n,n'-dimethyl-n-hydroxyethyl-3-nitro-p-phenylenediamine est-il sûr pendant l'allaitement ?
- Same rationale as pregnancy: no specific reproductive/breastmilk transfer or lactation studies for this CAS were found, no harmonised reproductive classification. Dermal exposure from cosmetic use of PPD‑type hair dyes is measurable; therefore a low but measurable exposure during breastfeeding is assigned in the absence of direct data. Regulatory prohibitions limit expected use in cosmetics in jurisdictions listing the CAS.
- n,n'-dimethyl-n-hydroxyethyl-3-nitro-p-phenylenediamine est-il sûr pour la peau de bébé ?
- No infant‑specific toxicology or dermal transfer data were found for CAS 10228-03-2. Following the scoring rules, because the adult exposure is judged low but measurable (e=1) and infants/0–3‑year skin has higher permeability and surface‑area‑to‑weight, exposure is increased by +1 (e=2). There is no direct evidence to increase hazard (h) or mechanism (m) for infants.
- Comment VeriMom évalue-t-il n,n'-dimethyl-n-hydroxyethyl-3-nitro-p-phenylenediamine ?
- VeriMom évalue n,n'-dimethyl-n-hydroxyethyl-3-nitro-p-phenylenediamine à 93/100 (pas de risques connus) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à n,n'-dimethyl-n-hydroxyethyl-3-nitro-p-phenylenediamine pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à n,n'-dimethyl-n-hydroxyethyl-3-nitro-p-phenylenediamine basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.