VeriMomn,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine est-il sûr pendant la grossesse ?
SCCS concluded the substance is not safe for use as a hair‑dye because genotoxicity could not be ruled out; the ingredient is a secondary amine prone to nitrosation (theoretical formation of nitrosamines, which are reproductive/developmental toxicants in some cases), so I assign a structural/class‑based reproductive concern (h=1) and a theoretical mechanism via nitrosation (m=1). Topical use in hair dyes at up to ~1% on‑head gives low but measurable exposure (e=1). Source: SCCS opinion and submissions; note secondary‑amine / nitrosation statement.
Alternatives sûres à n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine pendant la grossesse | VeriMom
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- n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine est-il sûr pendant la grossesse ?
- SCCS concluded the substance is not safe for use as a hair‑dye because genotoxicity could not be ruled out; the ingredient is a secondary amine prone to nitrosation (theoretical formation of nitrosamines, which are reproductive/developmental toxicants in some cases), so I assign a structural/class‑based reproductive concern (h=1) and a theoretical mechanism via nitrosation (m=1). Topical use in hair dyes at up to ~1% on‑head gives low but measurable exposure (e=1). Source: SCCS opinion and submissions; note secondary‑amine / nitrosation statement.
- n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine est-il sûr pendant l'allaitement ?
- Same rationale as for pregnancy: no direct reproductive/ lactation studies were found, but SCCS safety concerns (uncertainty about genotoxicity) and the compound’s propensity to nitrosate support a structural/theoretical concern (h=1, m=1). Dermal use leads to low but measurable exposure — breastfeeding exposure via maternal systemic absorption is therefore low but possible (e=1).
- n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine est-il sûr pour la peau de bébé ?
- No infant‑specific toxicology was located. Per instructions, because adult topical exposure is measurable (e=1) and infant skin has higher uptake, increase exposure score by +1 to e=2. Hazard and mechanism remain theoretical (h=1, m=1) in absence of direct developmental/infant data. SCCS restricted use for hair application; secondary‑amine nitrosation remains a contamination/indirect concern for infants.
- Comment VeriMom évalue-t-il n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine ?
- VeriMom évalue n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine à 67/100 (risque moyen) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à n,n'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.